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Interaction Summary

Homo sapiens

ABCA1

FLJ14958, HDLDT1, ABC1, ABC-1, MGC164864, CERP, MGC165011, TGD
ATP-binding cassette, sub-family A (ABC1), member 1
GO Process: 16 Terms
GO Function: 8 Terms
GO Component: 4 Terms

Gene Ontology Biological Process

  • Cdc42 protein signal transduction [IMP]
  • G-protein coupled receptor protein signaling pathway [IMP]
  • cholesterol efflux [IDA, IMP]
  • cholesterol homeostasis [IDA]
  • endosome transport [IDA]
  • high-density lipoprotein particle assembly [IMP]
  • interleukin-1 beta secretion [IMP]
  • intracellular cholesterol transport [IMP]
  • lysosome organization [IDA]
  • negative regulation of cholesterol storage [TAS]
  • negative regulation of foam cell differentiation [TAS]
  • phospholipid efflux [IDA, IMP]
  • phospholipid homeostasis [IMP]
  • platelet dense granule organization [IMP]
  • positive regulation of cAMP biosynthetic process [IMP]
  • reverse cholesterol transport [IMP]

Gene Ontology Molecular Function

  • anion transmembrane transporter activity [ISS]
  • apolipoprotein A-I receptor activity [IDA]
  • cholesterol binding [IC]
  • cholesterol transporter activity [IDA]
  • phospholipid binding [IC]
  • phospholipid transporter activity [IDA]
  • small GTPase binding [IPI]
  • syntaxin-13 binding [IPI]

Gene Ontology Cellular Component

  • integral to plasma membrane [IDA]
  • membrane fraction [IDA]
  • membrane raft [IDA]
  • phagocytic vesicle [IDA]

External Database Linkouts

HPRD | OMIM | Entrez Gene | RefSEQ | GenBank | UniprotKB
Download 9 Associations For This Protein
106537
9606
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