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Interaction Summary

Homo sapiens

PDGFA

PDGF1, PDGF-A
platelet-derived growth factor alpha isoform 2 preproprotein
GO Process: 13 Terms
GO Function: 6 Terms
GO Component: 4 Terms

Gene Ontology Biological Process

  • cell activation [TAS]
  • cell-cell signaling [TAS]
  • embryonic development [TAS]
  • negative chemotaxis [IDA]
  • negative regulation of phosphatidylinositol biosynthetic process [IDA]
  • negative regulation of platelet activation [IDA]
  • platelet-derived growth factor receptor signaling pathway [IDA]
  • positive regulation of DNA replication [IDA]
  • positive regulation of cell migration [IDA]
  • positive regulation of fibroblast proliferation [IDA]
  • regulation of actin cytoskeleton organization [TAS]
  • regulation of smooth muscle cell migration [IDA]
  • wound healing [TAS]

Gene Ontology Molecular Function

  • cell surface binding [IDA]
  • collagen binding [IDA]
  • platelet-derived growth factor binding [IPI]
  • platelet-derived growth factor receptor binding [IDA, IPI]
  • protein heterodimerization activity [IPI]
  • protein homodimerization activity [IDA]

Gene Ontology Cellular Component

  • cell surface [IDA]
  • extracellular region [EXP]
  • extracellular space [IDA]
  • platelet dense granule lumen [EXP]

External Database Linkouts

HPRD | OMIM | Entrez Gene | RefSEQ | GenBank | UniprotKB
Download 4 Associations For This Protein
111180
9606
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