Rattus norvegicus
HMGB1
Ac2-008, Hmg1
high mobility group box 1
GO Process (47)
GO Function (22)
GO Component (7)
Gene Ontology Biological Process
- DNA geometric change [IDA]
- V(D)J recombination [ISO]
- actin cytoskeleton reorganization [IMP]
- base-excision repair, DNA ligation [ISO]
- cell morphogenesis [IMP]
- cellular response to interleukin-1 [IEP]
- chemotaxis [IDA]
- chromatin remodeling [IBA]
- circadian rhythm [IEP]
- eye development [ISO]
- induction of positive chemotaxis [IDA]
- inflammatory response to antigenic stimulus [ISO]
- lung development [ISO]
- male-specific defense response to bacterium [IDA]
- myoblast proliferation [IMP]
- negative regulation of DNA replication [IDA]
- negative regulation of RNA polymerase II transcriptional preinitiation complex assembly [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- nervous system development [IMP]
- neuron projection development [IGI]
- positive regulation of DNA binding [ISO]
- positive regulation of apoptotic process [IMP, ISO]
- positive regulation of cell death [IMP]
- positive regulation of cell migration [IDA]
- positive regulation of cell proliferation [IDA]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of glycogen catabolic process [ISO]
- positive regulation of mesenchymal cell proliferation [IDA]
- positive regulation of mitotic cell cycle [IDA]
- positive regulation of myeloid cell apoptotic process [IDA]
- positive regulation of myeloid cell differentiation [ISO]
- positive regulation of myoblast differentiation [IMP]
- positive regulation of neuron projection development [IMP]
- positive regulation of protein kinase activity [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of smooth muscle cell migration [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of inflammatory response [IDA]
- regulation of transcription from RNA polymerase II promoter [ISO]
- regulation of transcription, DNA-templated [IBA]
- response to drug [IEP]
- response to glucocorticoid [ISO]
- response to glucose [IEP]
- response to heat [IEP]
- response to insulin [IEP]
- response to interferon-gamma [IMP]
- response to lipopolysaccharide [IEP]
Gene Ontology Molecular Function- 5S rRNA binding [IDA]
- DNA binding, bending [IDA, ISO]
- RAGE receptor binding [IMP, IPI]
- bent DNA binding [IDA]
- calcium-dependent protein kinase regulator activity [ISO]
- chromatin binding [IBA]
- crossed form four-way junction DNA binding [IDA]
- cytokine activity [IDA, ISO]
- double-stranded DNA binding [IDA]
- four-way junction DNA binding [IDA]
- glycolipid binding [IDA]
- heparin binding [IDA, TAS]
- open form four-way junction DNA binding [IDA]
- peptide binding [IDA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein dimerization activity [IDA]
- protein kinase activator activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- single-stranded DNA binding [IDA]
- transcription factor binding [IDA, ISO]
- 5S rRNA binding [IDA]
- DNA binding, bending [IDA, ISO]
- RAGE receptor binding [IMP, IPI]
- bent DNA binding [IDA]
- calcium-dependent protein kinase regulator activity [ISO]
- chromatin binding [IBA]
- crossed form four-way junction DNA binding [IDA]
- cytokine activity [IDA, ISO]
- double-stranded DNA binding [IDA]
- four-way junction DNA binding [IDA]
- glycolipid binding [IDA]
- heparin binding [IDA, TAS]
- open form four-way junction DNA binding [IDA]
- peptide binding [IDA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- protein dimerization activity [IDA]
- protein kinase activator activity [ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding transcription factor activity [ISO]
- single-stranded DNA binding [IDA]
- transcription factor binding [IDA, ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 7
- Interactions 7
- Network