Rattus norvegicus
MSH2
mutS homolog 2
GO Process (34)
GO Function (27)
GO Component (6)
Gene Ontology Biological Process
- ATP catabolic process [IBA, ISO]
- B cell differentiation [ISO]
- B cell mediated immunity [ISO]
- DNA repair [ISO]
- cell cycle arrest [ISO]
- cellular response to DNA damage stimulus [ISO]
- determination of adult lifespan [ISO]
- double-strand break repair [IBA, ISO]
- germ cell development [ISO]
- in utero embryonic development [ISO]
- intra-S DNA damage checkpoint [IBA, ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IBA, ISO]
- isotype switching [IBA, ISO]
- maintenance of DNA repeat elements [IBA, ISO]
- male gonad development [ISO]
- meiotic gene conversion [IBA]
- meiotic mismatch repair [IBA]
- mismatch repair [ISO]
- negative regulation of DNA recombination [ISO]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of reciprocal meiotic recombination [IBA]
- oxidative phosphorylation [ISO]
- positive regulation of helicase activity [ISO]
- postreplication repair [IBA, ISO, ISS]
- response to UV-B [IBA, ISO]
- response to X-ray [IBA, ISO]
- response to amino acid [IEP]
- response to drug [IEP]
- response to organic cyclic compound [IEP]
- somatic hypermutation of immunoglobulin genes [IBA, ISO]
- somatic recombination of immunoglobulin gene segments [ISO]
- somatic recombination of immunoglobulin genes involved in immune response [ISO]
- spermatogenesis [IEP]
Gene Ontology Molecular Function- ADP binding [ISO]
- ATP binding [ISO]
- ATPase activity [ISO]
- DNA binding [ISO, ISS]
- DNA-dependent ATPase activity [IBA]
- MutLalpha complex binding [ISO]
- Y-form DNA binding [IBA]
- centromeric DNA binding [ISO]
- damaged DNA binding [IBA, ISO]
- dinucleotide insertion or deletion binding [ISO]
- dinucleotide repeat insertion binding [ISO]
- double-strand/single-strand DNA junction binding [IBA]
- double-stranded DNA binding [ISO]
- enzyme binding [ISO]
- four-way junction DNA binding [IBA, ISO]
- guanine/thymine mispair binding [IBA, ISO]
- heteroduplex DNA loop binding [IBA]
- magnesium ion binding [ISO]
- mismatched DNA binding [ISO]
- oxidized purine DNA binding [ISO]
- protein C-terminus binding [ISO]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
- single base insertion or deletion binding [IBA]
- single guanine insertion binding [ISO]
- single thymine insertion binding [ISO]
- single-stranded DNA binding [ISO]
- ADP binding [ISO]
- ATP binding [ISO]
- ATPase activity [ISO]
- DNA binding [ISO, ISS]
- DNA-dependent ATPase activity [IBA]
- MutLalpha complex binding [ISO]
- Y-form DNA binding [IBA]
- centromeric DNA binding [ISO]
- damaged DNA binding [IBA, ISO]
- dinucleotide insertion or deletion binding [ISO]
- dinucleotide repeat insertion binding [ISO]
- double-strand/single-strand DNA junction binding [IBA]
- double-stranded DNA binding [ISO]
- enzyme binding [ISO]
- four-way junction DNA binding [IBA, ISO]
- guanine/thymine mispair binding [IBA, ISO]
- heteroduplex DNA loop binding [IBA]
- magnesium ion binding [ISO]
- mismatched DNA binding [ISO]
- oxidized purine DNA binding [ISO]
- protein C-terminus binding [ISO]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
- single base insertion or deletion binding [IBA]
- single guanine insertion binding [ISO]
- single thymine insertion binding [ISO]
- single-stranded DNA binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
249587
10116
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- Interactions 1
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