Rattus norvegicus
EGLN1
HIF-PH2, HPH-2, PHD-2, PHD2
egl-9 family hypoxia-inducible factor 1
GO Process (12)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
- cardiac muscle tissue morphogenesis [ISO]
- heart trabecula formation [ISO]
- labyrinthine layer development [ISO]
- negative regulation of cAMP catabolic process [IMP]
- negative regulation of cyclic-nucleotide phosphodiesterase activity [IMP]
- negative regulation of sequence-specific DNA binding transcription factor activity [IDA, ISO]
- oxygen homeostasis [ISO]
- peptidyl-proline hydroxylation to 4-hydroxy-L-proline [ISO]
- regulation of angiogenesis [ISO, ISS]
- response to hypoxia [IDA, ISO]
- response to nitric oxide [ISO, ISS]
- ventricular septum morphogenesis [ISO]
Gene Ontology Molecular Function- enzyme binding [IPI]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [ISO]
- peptidyl-proline 4-dioxygenase activity [ISO]
- peptidyl-proline dioxygenase activity [IDA]
- enzyme binding [IPI]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors [ISO]
- peptidyl-proline 4-dioxygenase activity [ISO]
- peptidyl-proline dioxygenase activity [IDA]
Download Curated Data for this Protein
259192
10116
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- Interactors 1
- Interactions 2
- Network