Saccharomyces cerevisiae (S288c)

FPR4

peptidylprolyl isomerase FPR4, L000004352, YLR449W
Peptidyl-prolyl cis-trans isomerase (PPIase); nuclear proline isomerase; affects expression of multiple genes via its role in nucleosome assembly; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones; PPIase domain acts as a transcriptional repressor when tethered to DNA by lexA, and repressor activity is dependent on PPIase activity; FPR4 has a paralog, FPR3, that arose from the whole genome duplication
UBI
PHO
SUMO

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
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  • PTM Sites (7)