Saccharomyces cerevisiae

DRS2

FUN38, SWA3, YAL026C

Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease

GO Process: 6 Terms

GO Function: 2 Terms

GO Component: 1 Terms

Gene Ontology Biological Process

endocytosis [IGI]

intracellular protein transport [IGI]

phospholipid translocation [IMP]

post-Golgi vesicle-mediated transport [IGI, IMP]

ribosomal small subunit assembly [IMP]

transmembrane transport [ISS]

Gene Ontology Molecular Function

ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism [ISS]
phospholipid-translocating ATPase activity [IGI, IMP]

Gene Ontology Cellular Component

trans-Golgi network [IDA]

External Database Linkouts

Download 133 Associations For This Protein

31740

4932

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Summary
Table

Interaction Summary