Saccharomyces cerevisiae (S288c)

SAN1

ubiquitin-protein ligase SAN1, L000001800, YDR143C
Ubiquitin-protein ligase; involved in proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition; prefers a window of exposed hydrophobicity that causes a particular level of protein insolubility, suggesting that San1p evolved to target highly aggregation-prone proteins
UBI

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 124 Published Interactions For This Protein
32197
559292
  • Stats & Options
Switch View:
  • Interactors (93)
  • Interactions (124)
  • Network
  • PTM Sites (1)