Saccharomyces cerevisiae (S288c)

UBC4

E2 ubiquitin-conjugating protein UBC4, L000002407, YBR082C
Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication
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SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
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  • Interactors (265)
  • Interactions (443)
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  • PTM Sites (1)