Saccharomyces cerevisiae

BUB1

YGR188C
Protein kinase involved in the cell cycle checkpoint into anaphase; forms complex with Mad1p and Bub3p crucial to preventing cell cycle progression into anaphase in the presence of spindle damage; CDC28-mediated phosphorylation at Bub1p-T566 is important for its degradation in anaphase and adaptation of the checkpoint to prolonged mitotic arrest, but not to its kinase activity or chromosome segregation function; associates with centromere DNA via Skp1p
P

External Database Linkouts

SGD | Entrez Gene | RefSEQ | GenBank | UniprotKB | PhosphoGRID
Download 473 Associations For This Protein
33440
559292
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  • 7 PTM Sites