Saccharomyces cerevisiae (S288c)

HMG1

hydroxymethylglutaryl-CoA reductase (NADPH) HMG1, L000000789, YML075C
HMG-CoA reductase; catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; one of two isozymes; localizes to the nuclear envelope; overproduction induces the formation of karmellae; forms foci at the nuclear periphery upon DNA replication stress; HMG1 has a paralog, HMG2, that arose from the whole genome duplication
P
GO Process: 2 Terms
GO Function: 1 Terms
GO Component: 4 Terms

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 161 Published Interactions For This Protein
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  • PTM Sites (7)