Saccharomyces cerevisiae (S288c)

PIF1

TST1, DNA helicase PIF1, L000001435, YML061C
DNA helicase, potent G-quadruplex DNA binder/unwinder; possesses strand annealing activity; promotes DNA synthesis during break-induced replication; important for crossover recombination; translation from different start sites produces mitochondrial and nuclear forms; nuclear form is a catalytic inhibitor of telomerase; mitochondrial form involved in DNA repair and recombination; mutations affect Zn, Fe homeostasis; regulated by Rad53p-dependent phosphorylation in rho0 cells
PHO
SUMO

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 169 Published Interactions For This Protein
35105
559292
  • Stats & Options
Switch View:
  • Interactors (105)
  • Interactions (169)
  • Network
  • PTM Sites (6)