Saccharomyces cerevisiae (S288c)

TOP2

TOR3, TRF3, DNA topoisomerase 2, L000002320, YNL088W
Topoisomerase II; relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis; required for replication slow zone (RSZ) breakage following Mec1p inactivation
P

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 113 Published Interactions For This Protein
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