Saccharomyces cerevisiae (S288c)

RTT107

ESC4, L000004424, YHR154W
Protein implicated in Mms22-dependent DNA repair during S phase; involved in recruiting the SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress
UBI
PHO
SUMO
GO Process (2)
GO Function (0)
GO Component (2)

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 508 Published Interactions For This Protein
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  • Interactors (352)
  • Interactions (508)
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  • PTM Sites (23)