Saccharomyces cerevisiae (S288c)

SLX8

SUMO-targeted ubiquitin ligase complex subunit SLX8, YER116C
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; stimulated by prior attachment of SUMO to the substrate; contains a C-terminal RING domain; forms nuclear foci upon DNA replication stress; null mutants are aneuploid, have a metaphase delay, and spindle defects including: mispositioned spindles, fish hook spindles, and aberrant spindle kinetics; required for maintenance of genome integrity like human ortholog RNF4
P
GO Process: 4 Terms
GO Function: 1 Terms
GO Component: 3 Terms

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
Download 485 Published Interactions For This Protein
36861
559292
  • Stats & Options
Switch View:
  • Interactors (325)
  • Interactions (485)
  • Network
  • PTM Sites (4)