Saccharomyces cerevisiae (S288c)

SLX8

SUMO-targeted ubiquitin ligase complex subunit SLX8, YER116C
Subunit of Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; stimulated by prior attachment of SUMO to the substrate; contains a C-terminal RING domain; forms nuclear foci upon DNA replication stress; null mutants are aneuploid, have a metaphase delay, and spindle defects including: mispositioned spindles, fish hook spindles, and aberrant spindle kinetics; required for maintenance of genome integrity like human ortholog RNF4
PHO
GO Process (4)
GO Function (1)
GO Component (3)

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB | PhosphoGRID
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  • PTM Sites (4)