BioGRID Funding And Partners

BioGRID Partner National Institutes of Health NIH BioGRID Partner Canadian Inststitutes of Health Research BioGRID Partner Genome Quebec BioGRID Partner Mount Sinai Hospital BioGRID Partner Princeton University BioGRID Partner Universite de Montreal BioGRID Partner Saccharomyces Genome Database BioGRID Partner University of Edinburgh BioGRID Partner IMEX

Areas of Interest to Help You Get Started

Build and Download Interaction Datasets

Create custom interaction datasets by protein or by publication. You can also download our entire dataset in a wide variety of standard formats.

Link To Us or Submit Interactions

Send us your datasets or link to the BioGRID directly from your own website or database. Full details on how to contribute are available here.

Online Tools and Resources

We've developed tools that make use of BioGRID data. Check out the list of tools to see if we can help you work with our data.

View Our Interaction Statistics

Find out how many organisms, proteins, publications, and interactions are available in the current release of the BioGRID.

Latest News

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,699 publications. These additions bring our total number of non-redundant interactions to 822,766, raw interactions to 1,052,258, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: January 30, 2016 - 3:19 am

Newly released BioGRID protocol papers demonstrate techniques in which our data are utilized as a resource for the study of biological interaction data in yeast. The following publications are available now:

Use of the BioGRID Database for Analysis of Yeast Protein and Genetic Interactions
Oughtred R et. al.
Cold Spring Harb Protoc. 2016

BioGRID: A Resource for Studying Biological Interactions in Yeast.
Oughtred R et al.
Cold Spring Harb Protoc. 2016

Posted: January 5, 2016 - 6:43 pm

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,519 publications. These additions bring our total number of non-redundant interactions to 757,476, raw interactions to 980,467, non-redundant chemical associations to 11,694, raw chemical associations to 27,501, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: January 1, 2016 - 3:19 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,346 publications. These additions bring our total number of non-redundant interactions to 749,213, raw interactions to 971,115, non-redundant chemical associations to 11,329, raw chemical associations to 27,034, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: December 1, 2015 - 6:19 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,326 publications. These additions bring our total number of non-redundant interactions to 749,199, raw interactions to 971,027, non-redundant chemical associations to 11,329, raw chemical associations to 27,034, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: November 1, 2015 - 4:18 am

The BioGRID's curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,218 publications. These additions bring our total number of non-redundant interactions to 614,457, raw interactions to 834,948, non-redundant chemical associations to 11,329, raw chemical associations to 27,034, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: October 1, 2015 - 7:18 am

The BioGRID‘s curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 55,018 publications. These additions bring our total number of non-redundant interactions to 597,636, raw interactions to 812,281, non-redundant chemical associations to 11,329, raw chemical associations to 27,034, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: September 1, 2015 - 2:44 pm

The BioGRID‘s curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 54,676 publications. These additions bring our total number of non-redundant interactions to 583,703, raw interactions to 796,767, non-redundant chemical associations to 11,329, raw chemical associations to 27,034, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: August 1, 2015 - 8:55 am

The BioGRID‘s curated set of physical and genetic interactions has been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 54,430 publications. These additions bring our total number of non-redundant interactions to 576,636, raw interactions to 788,169, non-redundant chemical associations to 11,329, raw chemical associations to 27,034, Unique PTM Sites to 19,981, and Un-Assigned PTMs to 18,578. New curated data will be added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest interaction statistics. To download these data, visit our download page.

Posted: July 1, 2015 - 7:58 pm

The BioGRID was updated today to our newest release designated BioGRID 3.4. This update includes several bug fixes and user interface improvements as well as some new features. The following is a short list of some of the changes:

  • Improved Post-Translational Modification View. We have made many changes to our post-translational modification (PTM) view in order to become more user-friendly and to better support non-assigned PTMs and PTMs assigned to isoform proteins. If available, these will be accessible via the “PTM Sites” tab in the “Switch View” section of our interaction summaries. Examples: STE11, TP53, NEDD8, STE20, and Breitkreutz A (2010) et al. (PUB:20489023).
  • New Individual Interaction View. As requested by many users, you can now link to individual interaction pages within the BioGRID. These pages list all of the details for a single interaction and can be reached using a URL structure of http://thebiogrid.org/interaction/[interaction id]. The following are a few examples: STE11-STE50, DAD1-FUS1, TP53-MDM2, and PTC-BABO.
  • Improved Source Database Attribution. All interactions now prominently display a “Curated By” reference indicating the source database responsible for originally curating the interaction from the literature. This attribution has been available since the beginning, but was displayed via a tooltip. Interactions not originally curated by the BioGRID will now link directly to the original source without requiring a visit to the tooltip. Example: Bazooka.
  • More Statistics. On our statistics page we have included (in addition to our physical and genetic interaction statistics) new tables displaying chemical association statistics and post translational modification statistics for the current BioGRID release.
  • Graphical User Interface Updates. We’ve made several user interface updates to improve the functionality of the BioGRID and to reduce page load times.
  • Download File Improvements. We’ve fixed several issues with our download files to improve compatibility with standards. In addition, we’ve also included a new download file format for Chemical Associations. This file can be downloaded via our downloads page. For more information on this new format, visit our Help Wiki.
  • Updated Wiki Documentation. We’ve updated several pages in our Wiki to provide updated documentation on a variety of topics.

These are just some of the many improvements now available in BioGRID 3.4. We have many additional features already under development for version 3.5 that will expand on this functionality and ensure the BioGRID remains a useful resource for the biological community. If you have any questions about this build or suggestions for future builds, please feel free to contact us at biogridadmin@gmail.com.

Posted: June 1, 2015 - 8:03 pm