Caenorhabditis elegans
LPIN-1
CELE_H37A05.1, H37A05.1
lpin-1 encodes a putative phosphatidic acid phosphatase orthologous to budding yeast PAH1 and human LPIN1 (OMIM:605518), LPIN2 (OMIM:605519, mutated in Majeed syndrome), and LPIN3 (OMIM:605520); lpin-1 is expressed in vulval muscle; in mass RNAi assays, lpin-1 is required for the osmotic integrity of eggs and for normal larval growth, body thickness, locomotion, and fertility; by orthology, LPIN-1 is expected to be dephosphorylated by SCPL-2.
GO Process (20)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- apoptotic process [IMP]
- cellular component organization [IMP]
- dephosphorylation [ISS]
- embryo development [IMP]
- embryo development ending in birth or egg hatching [IMP]
- endoplasmic reticulum organization [IMP]
- lamin depolymerization [IMP]
- lipid storage [IMP]
- locomotion [IMP]
- mitotic sister chromatid segregation [IMP]
- mitotic spindle organization [IMP]
- nematode larval development [IMP]
- nuclear envelope disassembly [IMP]
- nuclear envelope reassembly [IMP]
- nucleus organization [IMP]
- positive regulation of multicellular organism growth [IMP]
- protein localization to nucleus [IMP]
- regulation of nuclear division [IMP]
- reproduction [IMP]
- secretion by cell [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
44869
6239
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- Interactors 2
- Interactions 2
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