Saccharomyces cerevisiae (S288c)


MFP1, TRG1, protein disulfide isomerase PDI1, L000001360, YCL043C
Protein disulfide isomerase; multifunctional protein of ER lumen, essential for formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds; key regulator of Ero1p; forms complex with Mnl1p that has exomannosidase activity, processing unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2, promoting degradation in unfolded protein response; PDI1 has a paralog, EUG1, that arose from the whole genome duplication
GO Process (1)
GO Function (4)
GO Component (1)

External Database Linkouts

SGD | Entrez Gene | RefSeq | UniprotKB
Download 353 Published Interactions For This Protein
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  • Interactors (295)
  • Interactions (353)
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  • PTM Sites (1)