Caenorhabditis elegans

PRO-2

CELE_C07E3.2, C07E3.2
pro-2 encodes the C. elegans ortholog of Saccharomyces cerevisiae Noc2p, which is required for intranuclear ribosome maturation and transport; in C. elegans, pro-2 activity is essential for larval growth, somatic gonad development, regulation of germline development and proliferation, and hence, fertility; by virtue of its similarity to Noc2p, PRO-2 is predicted to be a component of two heterodimeric intranuclear complexes that associate with, and aid in maturation of, different preribosomal particles.
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  • Interactors 4
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