Caenorhabditis elegans

KIN-19

CELE_C03C10.1, C03C10.1
kin-19 encodes a serine/threonine kinase orthologous to Casein Kinase I (CKI); in the early embryo, kin-19 is a component of both the non-canonical Wnt signaling pathway that regulates endoderm formation in the early embryo as well as the Wnt spindle orientation pathway; during larval development, kin-19 functions in a non-canonical Wnt signaling pathway to control asymmetric division and fate specification in epidermal seam cells; kin-19 also functions with, or in parallel to, the heterochronic pathway to regulate loss of self-renewal and terminal differentiation of epidermal seam cells; KIN-19 localizes to centrosomes, the cytoplasm, and the nucleus.
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  • Interactors 5
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