Caenorhabditis elegans

PAA-1

CELE_F48E8.5, F48E8.5
paa-1 encodes the sole C. elegans homolog of PR65, the structural subunit of protein phosphatase 2A (PP2A); paa-1 is an essential gene, required in RNAi assays for embryonic viability, fertility, and cuticular integrity; PAA-1 protein physically interacts with LET-92, the PP2A catalytic subunit, and with RSA-1, a PP2A regulatory subunit; PAA-1 also physically interacts with SMG-5; PAA-1 localizes to centrosomes, the mitotic spindle, P granules, and the nuclear envelope; PAA-1 levels at the centrosome are decreased in rsa-1 mutant animals.
Download Curated Data for this Protein
40979
6239
Switch View:
  • Interactors 16
  • Interactions 19
  • Network