Caenorhabditis elegans

KNL-3

CELE_T10B5.6, T10B5.6
knl-3 encodes a novel protein; KNL-3 activity is essential for formation of a functional kinetochore and thus, for proper chromosome segregation and spindle pole separation; KNL-3 localizes to kinetochores throughout mitosis and this localization requires the activity of HCP-4 (CENP-C), a conserved kinetochore component that likely directs kinetochore assembly; KNL-3 copurifies with a group of 10 closely interacting kinetochore proteins that includes KNL-1, NDC-80, MIS-12, HIM-10, and KBP-1, -2, -3, -4, and-5; KNL-3 also copurifies with HCP-4(CENP-C).
GO Process (6)
GO Function (1)
GO Component (1)

External Database Linkouts

WormBase | Entrez Gene | RefSeq | UniprotKB
Download 18 Published Interactions For This Protein
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  • Interactors (13)
  • Interactions (18)
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