BAIT
NRBF2
COPR1, COPR2, NRBF-2, RP11-144G16.2
nuclear receptor binding factor 2
GO Process (2)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Homo sapiens
PREY
RXRA
NR2B1
retinoid X receptor, alpha
GO Process (13)
GO Function (14)
GO Component (5)
Gene Ontology Biological Process
- cellular lipid metabolic process [TAS]
- cholesterol metabolic process [TAS]
- gene expression [TAS]
- modulation by virus of host morphology or physiology [IDA]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- peroxisome proliferator activated receptor signaling pathway [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- protein homotetramerization [IDA]
- response to retinoic acid [IMP]
- retinoic acid receptor signaling pathway [IMP]
- small molecule metabolic process [TAS]
- transcription initiation from RNA polymerase II promoter [TAS]
- vitamin metabolic process [TAS]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- enzyme binding [IPI]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- retinoic acid receptor activity [TAS]
- retinoic acid-responsive element binding [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [TAS]
- transcription regulatory region DNA binding [IDA]
- vitamin D receptor binding [IPI]
- vitamin D response element binding [IDA]
- DNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- enzyme binding [IPI]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [IDA]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- retinoic acid receptor activity [TAS]
- retinoic acid-responsive element binding [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [TAS]
- transcription regulatory region DNA binding [IDA]
- vitamin D receptor binding [IPI]
- vitamin D response element binding [IDA]
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Nuclear receptor binding factor-2 (NRBF-2), a possible gene activator protein interacting with nuclear hormone receptors.
A protein named nuclear receptor binding factor-2 (NRBF-2) was identified by yeast two-hybrid screening, as an interaction partner of peroxisome proliferator-activated receptor alpha as well as several other nuclear receptors. NRBF-2 exhibited a gene activation function, when tethered to a heterologous DNA binding domain, in both mammalian cells and yeast. ... [more]
Biochim. Biophys. Acta Jan. 31, 2000; 1490(1);189-97 [Pubmed: 10786636]
Throughput
- Low Throughput
Curated By
- BioGRID