BAIT

MSC

ABF-1, ABF1, MYOR, bHLHa22
musculin
GO Process (1)
GO Function (2)
GO Component (0)
Homo sapiens
PREY

ID2

GIG8, ID2A, ID2H, bHLHb26
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
GO Process (25)
GO Function (2)
GO Component (7)

Gene Ontology Molecular Function

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Characterization of a basic helix-loop-helix protein, ABF-1: nuclear localization, transcriptional properties, and interaction with Id-2.

Wong J, Funes-Duran M, Ahlberg J, Round J, O'Connell R, Miller R, Chen E, Richmond PA, Vierra CA

The activated B-cell factor (ABF)-1 cDNA was initially isolated from Epstein-Barr virus (EBV)-infected B cells and codes for a DNA-binding protein belonging to the basic helix-loop-helix (bHLH) family of transcription factors. In this study, we characterized the nuclear localization signal of ABF-1, mapped two distinct transcriptional repression domains, and identified one ABF-1-interacting protein, Id-2. By examining the subcellular location of ... [more]

DNA Cell Biol. Aug. 01, 2001; 20(8);465-71 [Pubmed: 11560778]

Throughput

  • Low Throughput

Curated By

  • BioGRID