BAIT
CG6506
Dmel\CG6506, Spt7, dSpt7, Dmel_CG6506
CG6506 gene product from transcript CG6506-RA
GO Process (0)
GO Function (0)
GO Component (2)
Gene Ontology Cellular Component
Drosophila melanogaster
PREY
EN
153867_at, Apa, CG9015, Dmel\CG9015, EnR, Eng, Engr, Engrailed, Engrailed/Invected, Es, V, en1, spa2, spt, Dmel_CG9015
engrailed
GO Process (28)
GO Function (5)
GO Component (1)
Gene Ontology Biological Process
- analia development [TAS]
- anterior commissure morphogenesis [IMP]
- anterior head segmentation [TAS]
- anterior/posterior lineage restriction, imaginal disc [TAS]
- anterior/posterior pattern specification, imaginal disc [TAS]
- axon guidance [IMP]
- central nervous system development [NAS]
- compartment pattern specification [NAS, TAS]
- genital disc anterior/posterior pattern formation [IEP, TAS]
- genital disc development [IMP]
- gonad development [IMP]
- imaginal disc pattern formation [TAS]
- imaginal disc-derived female genitalia development [TAS]
- imaginal disc-derived male genitalia development [TAS]
- imaginal disc-derived wing vein specification [IMP]
- negative regulation of gene expression [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [NAS]
- neuroblast fate determination [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- posterior compartment specification [TAS]
- posterior head segmentation [TAS]
- regulation of gene expression [IMP]
- segment polarity determination [NAS, TAS]
- spiracle morphogenesis, open tracheal system [IMP]
- trunk segmentation [TAS]
- ventral midline development [IMP]
- wing disc anterior/posterior pattern formation [TAS]
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- enhancer sequence-specific DNA binding [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISS]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- enhancer sequence-specific DNA binding [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISS]
Drosophila melanogaster
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
A protein interaction map of Drosophila melanogaster.
Drosophila melanogaster is a proven model system for many aspects of human biology. Here we present a two-hybrid-based protein-interaction map of the fly proteome. A total of 10,623 predicted transcripts were isolated and screened against standard and normalized complementary DNA libraries to produce a draft map of 7048 proteins and 20,405 interactions. A computational method of rating two-hybrid interaction confidence ... [more]
Science Dec. 05, 2003; 302(5651);1727-36 [Pubmed: 14605208]
Throughput
- High Throughput
Curated By
- BioGRID