Homo sapiens
ACVR1
ACTRI, ACVR1A, ACVRLK2, ALK2, FOP, SKR1, TSRI
activin A receptor, type I
GO Process (22)
GO Function (11)
GO Component (2)
Gene Ontology Biological Process
- BMP signaling pathway [IDA]
- G1/S transition of mitotic cell cycle [IMP]
- activin receptor signaling pathway [IDA]
- atrial septum primum morphogenesis [IMP]
- cardiac muscle cell fate commitment [IMP]
- embryonic heart tube morphogenesis [IMP]
- endocardial cushion cell fate commitment [IMP]
- mitral valve morphogenesis [IMP]
- negative regulation of activin receptor signaling pathway [IMP]
- negative regulation of extrinsic apoptotic signaling pathway [IMP]
- negative regulation of signal transduction [IMP]
- pathway-restricted SMAD protein phosphorylation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- positive regulation of bone mineralization [IMP]
- positive regulation of determination of dorsal identity [IDA]
- positive regulation of osteoblast differentiation [IMP]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- protein phosphorylation [IDA]
- regulation of ossification [IMP]
- transforming growth factor beta receptor signaling pathway [IDA]
Gene Ontology Molecular Function- ATP binding [IDA]
- SMAD binding [IDA]
- activin binding [IDA]
- activin receptor activity, type I [IDA]
- peptide hormone binding [NAS]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- protein kinase activity [IDA]
- protein serine/threonine kinase activity [IDA]
- transforming growth factor beta binding [IDA]
- transmembrane receptor protein serine/threonine kinase activity [NAS]
- ATP binding [IDA]
- SMAD binding [IDA]
- activin binding [IDA]
- activin receptor activity, type I [IDA]
- peptide hormone binding [NAS]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- protein kinase activity [IDA]
- protein serine/threonine kinase activity [IDA]
- transforming growth factor beta binding [IDA]
- transmembrane receptor protein serine/threonine kinase activity [NAS]
Gene Ontology Cellular Component
Download Curated Data for this Protein
106605
9606
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- Interactors 113
- Interactions 147
- Chemical Interactions 3
- Network
- PTM Sites 17