Related Resources

The BioGRID Open Respository of CRISPR Screens (ORCS) is a publicly accessible database of CRISPR screens compiled through comprehensive curation of all genome-wide CRISPR screen data reported in the biomedical literature. ORCS is updated on a quarterly basis and is fully searchable by gene/protein, phenotype, cell line, authors, and other attributes. Each screen recorded in ORCS is accompanied by structured metadata annotation that captures salient CRISPR experimental details. All data in ORCS can be downloaded in standard formats.

BioGRID themed curation projects focus on specific biological processes with disease relevance. Core genes/proteins central to the process are assembled with expert input and relevant publications curated for biological interactions. Themed curation projects are updated monthly and additional projects are generated on a regular basis.

See current projects on Autism spectrum disorder, Alzheimer's Disease, COVID-19 Coronavirus, Fanconi Anemia, Glioblastoma, the Yeast Kinome, the Ubiquitin-Proteasome System and Autophagy. If you would like to suggest or participate in a new themed project, please contact support@thebiogrid.org

GIX is a browser extension that allows you to retrieve information about a gene product directly on any webpage simply by double clicking an official gene name, synonym or supported accession.

Partners

National Institutes of Health National Institutes of Health - Office of Research Infrastructure Programs Canadian Institutes of Health Research The Hospital for Sick Children (SickKids) Princeton University

Latest News

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 84,671 publications. These additions bring our total number of non-redundant interactions to 2,155,326, raw interactions to 2,770,929, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.233 Released
Posted: May 1, 2024 - 12:11 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 84,441 publications. These additions bring our total number of non-redundant interactions to 2,134,950, raw interactions to 2,746,236, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.232 Released
Posted: April 1, 2024 - 1:01 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 84,273 publications. These additions bring our total number of non-redundant interactions to 2,118,782, raw interactions to 2,727,399, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.231 Released
Posted: March 1, 2024 - 12:44 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 84,091 publications. These additions bring our total number of non-redundant interactions to 2,111,534, raw interactions to 2,718,549, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.230 Released
Posted: February 1, 2024 - 4:33 pm

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 83,957 publications. These additions bring our total number of non-redundant interactions to 2,105,957, raw interactions to 2,711,919, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.229 Released
Posted: January 1, 2024 - 7:39 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 83,750 publications. These additions bring our total number of non-redundant interactions to 2,091,895, raw interactions to 2,694,446, non-redundant chemical associations to 13,719, raw chemical associations to 31,144, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.228 Released
Posted: December 1, 2023 - 10:49 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 83,418 publications. These additions bring our total number of non-redundant interactions to 2,069,675, raw interactions to 2,658,532, non-redundant chemical associations to 13,347, raw chemical associations to 30,725, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.227 Released
Posted: November 1, 2023 - 8:25 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 83,191 publications. These additions bring our total number of non-redundant interactions to 2,064,135, raw interactions to 2,650,520, non-redundant chemical associations to 13,347, raw chemical associations to 30,725, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.226 Released
Posted: October 1, 2023 - 2:14 pm

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 82,951 publications. These additions bring our total number of non-redundant interactions to 2,056,006, raw interactions to 2,639,546, non-redundant chemical associations to 13,347, raw chemical associations to 30,725, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.225 Released
Posted: September 1, 2023 - 10:26 am

The BioGRID's curated set of data have been updated to include interactions, chemical associations, and post-translational modifications (PTM) from 82,750 publications. These additions bring our total number of non-redundant interactions to 2,054,274, raw interactions to 2,636,898, non-redundant chemical associations to 13,347, raw chemical associations to 30,725, Non-Redundant PTM Sites to 563,757 and Un-Assigned PTMs to 57,396.

New curated data are added in curation updates on a monthly basis. For a more comprehensive breakdown of our numbers, check out our latest statistics. To download these data, visit our download page or utilize our web service.

BioGRID Version 4.4.224 Released
Posted: August 1, 2023 - 7:18 am