Homo sapiens
ADAM8
CD156, CD156a, MS2
ADAM metallopeptidase domain 8
GO Process (25)
GO Function (6)
GO Component (11)
Gene Ontology Biological Process
- activation of MAPK activity involved in innate immune response [ISS]
- angiogenesis [ISS]
- cell morphogenesis [ISS]
- cellular response to hypoxia [IDA]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- inflammatory response [IDA]
- leukocyte migration involved in inflammatory response [ISS]
- lymphocyte chemotaxis [ISS]
- negative regulation of neuron apoptotic process [ISS]
- positive regulation of NF-kappaB transcription factor activity [ISS]
- positive regulation of T cell differentiation in thymus [ISS]
- positive regulation of acute inflammatory response [ISS]
- positive regulation of bone resorption [ISS]
- positive regulation of cell adhesion [ISS]
- positive regulation of eosinophil migration [ISS]
- positive regulation of fibronectin-dependent thymocyte migration [ISS]
- positive regulation of membrane protein ectodomain proteolysis [IDA]
- positive regulation of neutrophil extravasation [IDA]
- positive regulation of protein kinase B signaling [ISS]
- positive regulation of protein processing [NAS]
- positive regulation of protein secretion [IC]
- positive regulation of thymocyte apoptotic process [ISS]
- positive regulation of tumor necrosis factor (ligand) superfamily member 11 production [ISS]
- regulation of cell-cell adhesion [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- alpha9-beta1 integrin-ADAM8 complex [ISS]
- alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex [IDA]
- cell surface [IDA]
- cytoplasm [IDA]
- dense core granule membrane [IDA]
- integral component of plasma membrane [IDA]
- phagolysosome [IDA]
- plasma membrane [IDA, TAS]
- podosome [IDA]
- specific granule [IDA]
- tertiary granule [IDA]
Download Curated Data for this Protein
106615
9606
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- Interactors 3
- Interactions 3
- Network
- PTM Sites 4