Homo sapiens
F2RL1
GPR11, PAR2
coagulation factor II (thrombin) receptor-like 1
GO Process (46)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [TAS]
- T cell activation involved in immune response [ISS]
- chemokine (C-C motif) ligand 2 secretion [IDA]
- chemokine secretion [IDA]
- defense response to virus [IDA]
- establishment of endothelial barrier [IDA]
- interferon-gamma secretion [ISS]
- interleukin-1 beta secretion [IDA]
- interleukin-10 secretion [IDA]
- leukocyte migration [IDA]
- leukocyte proliferation [ISS]
- mature conventional dendritic cell differentiation [IDA, ISS]
- negative regulation of JNK cascade [IDA]
- negative regulation of chemokine secretion [IDA]
- negative regulation of toll-like receptor 3 signaling pathway [IMP]
- negative regulation of tumor necrosis factor-mediated signaling pathway [IDA]
- neutrophil activation [IDA]
- positive regulation of ERK1 and ERK2 cascade [IDA, ISS]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- positive regulation of JNK cascade [IDA]
- positive regulation of Rho protein signal transduction [IMP, ISS]
- positive regulation of actin filament depolymerization [IDA]
- positive regulation of cell migration [ISS]
- positive regulation of chemotaxis [ISS]
- positive regulation of cytokine secretion involved in immune response [IDA]
- positive regulation of cytosolic calcium ion concentration [IDA, ISS]
- positive regulation of eosinophil degranulation [IDA]
- positive regulation of glomerular filtration [ISS]
- positive regulation of interleukin-6 secretion [IDA]
- positive regulation of interleukin-8 secretion [IDA]
- positive regulation of leukocyte chemotaxis [IDA]
- positive regulation of neutrophil mediated killing of gram-negative bacterium [IDA]
- positive regulation of phagocytosis, engulfment [IDA]
- positive regulation of phosphatidylinositol 3-kinase signaling [ISS]
- positive regulation of positive chemotaxis [IDA]
- positive regulation of pseudopodium assembly [ISS]
- positive regulation of renin secretion into blood stream [ISS]
- positive regulation of superoxide anion generation [IDA]
- positive regulation of toll-like receptor 2 signaling pathway [IMP]
- positive regulation of toll-like receptor 3 signaling pathway [IMP]
- positive regulation of toll-like receptor 4 signaling pathway [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of vasodilation [ISS]
- regulation of I-kappaB kinase/NF-kappaB signaling [IDA]
- regulation of JNK cascade [IDA]
- regulation of blood coagulation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 205
- Interactions 224
- Network
- PTM Sites 17