Homo sapiens
TGFB2
LDS4, TGF-beta2
transforming growth factor, beta 2
GO Process (72)
GO Function (9)
GO Component (6)
Gene Ontology Biological Process
- SMAD protein import into nucleus [IDA]
- SMAD protein signal transduction [IBA]
- activation of protein kinase activity [IDA]
- angiogenesis [TAS]
- blood coagulation [TAS]
- cardiac epithelial to mesenchymal transition [IDA]
- cardiac muscle cell proliferation [IDA]
- cardioblast differentiation [IDA]
- catagen [IDA]
- cell cycle arrest [IDA]
- cell death [IDA]
- cell migration [IDA]
- cell morphogenesis [IDA]
- cell proliferation [TAS]
- cell-cell junction organization [IDA]
- cell-cell signaling [TAS]
- collagen fibril organization [IDA]
- dopamine biosynthetic process [ISS]
- embryo development [TAS]
- embryonic digestive tract development [IEP]
- epithelial to mesenchymal transition [IDA, TAS]
- extracellular matrix organization [TAS]
- extrinsic apoptotic signaling pathway [IDA]
- eye development [IDA]
- generation of neurons [TAS]
- glial cell migration [IDA]
- hair follicle development [IDA, ISS]
- hair follicle morphogenesis [ISS]
- heart development [IDA]
- heart morphogenesis [IDA]
- hemopoiesis [ISS]
- negative regulation of alkaline phosphatase activity [IDA]
- negative regulation of cell growth [IDA]
- negative regulation of cell proliferation [IDA]
- negative regulation of epithelial cell proliferation [IDA, IMP]
- negative regulation of immune response [TAS]
- negative regulation of macrophage cytokine production [IDA]
- neuron development [ISS]
- neutrophil chemotaxis [ISS, TAS]
- odontogenesis [NAS]
- pathway-restricted SMAD protein phosphorylation [IDA]
- platelet activation [TAS]
- platelet degranulation [TAS]
- positive regulation of cardioblast differentiation [IDA]
- positive regulation of catagen [IDA]
- positive regulation of cell adhesion mediated by integrin [IDA]
- positive regulation of cell cycle [ISS]
- positive regulation of cell growth [IDA]
- positive regulation of cell proliferation [IDA]
- positive regulation of epithelial cell migration [IDA]
- positive regulation of epithelial to mesenchymal transition [IDA]
- positive regulation of heart contraction [IDA]
- positive regulation of immune response [ISS]
- positive regulation of integrin biosynthetic process [IDA]
- positive regulation of neuron apoptotic process [IDA]
- positive regulation of ossification [IEP]
- positive regulation of pathway-restricted SMAD protein phosphorylation [IBA]
- positive regulation of phosphatidylinositol 3-kinase signaling [IDA]
- positive regulation of protein secretion [IDA]
- positive regulation of stress-activated MAPK cascade [IDA]
- protein phosphorylation [IDA]
- regulation of transforming growth factor beta2 production [IMP]
- response to drug [IDA]
- response to hypoxia [IMP]
- response to progesterone [IDA]
- response to wounding [IEP]
- salivary gland morphogenesis [IEP]
- signal transduction by phosphorylation [IDA]
- somatic stem cell division [ISS]
- transforming growth factor beta receptor signaling pathway [IDA]
- uterine wall breakdown [TAS]
- wound healing [ISS]
Gene Ontology Molecular Function- beta-amyloid binding [IDA]
- cytokine activity [TAS]
- protein binding [IPI]
- protein heterodimerization activity [TAS]
- protein homodimerization activity [IDA]
- receptor binding [IMP]
- receptor signaling protein serine/threonine kinase activity [IDA]
- transforming growth factor beta receptor binding [IDA]
- type II transforming growth factor beta receptor binding [IDA, IPI]
- beta-amyloid binding [IDA]
- cytokine activity [TAS]
- protein binding [IPI]
- protein heterodimerization activity [TAS]
- protein homodimerization activity [IDA]
- receptor binding [IMP]
- receptor signaling protein serine/threonine kinase activity [IDA]
- transforming growth factor beta receptor binding [IDA]
- type II transforming growth factor beta receptor binding [IDA, IPI]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 48
- Interactions 51
- Network
- PTM Sites 7