BioGRID3.2
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Interaction Summary

Gene / Identifier Search

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Homo sapiens

SHANK3

SPANK-2, DEL22q13.3, PSAP2, SCZD15, PROSAP2
SH3 and multiple ankyrin repeat domains protein 3
GO Process: 14 Terms
GO Function: 5 Terms
GO Component: 3 Terms

Gene Ontology Biological Process

  • brain morphogenesis [ISS]
  • dendritic spine morphogenesis [ISS]
  • locomotory exploration behavior [ISS]
  • negative regulation of cell volume [ISS]
  • positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [ISS]
  • positive regulation of excitatory postsynaptic membrane potential [ISS]
  • positive regulation of long-term neuronal synaptic plasticity [ISS]
  • positive regulation of synapse structural plasticity [ISS]
  • positive regulation of synaptic transmission, glutamatergic [ISS]
  • postsynaptic density assembly [ISS]
  • regulation of behavioral fear response [ISS]
  • social behavior [ISS]
  • striatal medium spiny neuron differentiation [ISS]
  • vocalization behavior [ISS]

Gene Ontology Molecular Function

  • GKAP/Homer scaffold activity [ISS]
  • ionotropic glutamate receptor binding [ISS]
  • protein C-terminus binding [ISS]
  • protein binding [IPI]
  • scaffold protein binding [ISS]

Gene Ontology Cellular Component

  • neuron spine [ISS]
  • plasma membrane [ISS]
  • postsynaptic density [ISS]

External Database Linkouts

HGNC | OMIM | Ensembl | Entrez Gene | RefSEQ | GenBank | UniprotKB
Download 14 Associations For This Protein
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