Mus musculus
SMAD1
AI528653, Madh1, Madr1, Mlp1, MusMLP
SMAD family member 1
GO Process (25)
GO Function (11)
GO Component (6)
Gene Ontology Biological Process
- BMP signaling pathway [IGI, IMP, ISO, TAS]
- MAPK cascade [IMP, ISO]
- SMAD protein complex assembly [ISO]
- bone development [IGI]
- cardiac muscle cell proliferation [IGI, IMP]
- cartilage development [IGI]
- cellular response to BMP stimulus [IGI]
- cellular response to organic cyclic compound [IDA]
- gamete generation [IMP]
- hindbrain development [IMP]
- homeostatic process [IMP]
- mesodermal cell fate commitment [IGI]
- midbrain development [IMP]
- negative regulation of cell proliferation [IMP]
- osteoblast fate commitment [IGI]
- positive regulation of cartilage development [IDA]
- positive regulation of cell differentiation [ISO]
- positive regulation of gene expression [IMP, ISO]
- positive regulation of osteoblast differentiation [IGI]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus [IGI]
- protein phosphorylation [IDA]
- regulation of transcription from RNA polymerase II promoter [IDA]
- response to drug [ISO]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- I-SMAD binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- co-SMAD binding [ISO]
- identical protein binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA]
- protein kinase binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- I-SMAD binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- co-SMAD binding [ISO]
- identical protein binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA]
- protein kinase binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
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- Interactors 36
- Interactions 44
- Network
- PTM Sites 1