Mus musculus
ASCL1
AI225900, ASH1, Mash1, bHLHa46
achaete-scute complex homolog 1 (Drosophila)
GO Process (60)
GO Function (12)
GO Component (2)
Gene Ontology Biological Process
- Notch signaling pathway [IGI, ISO]
- adrenal chromaffin cell differentiation [IMP]
- carotid body glomus cell differentiation [IMP]
- cell differentiation [IMP]
- cell maturation [IMP]
- central nervous system neuron development [IGI, IMP]
- cerebral cortex development [IMP]
- commitment of neuronal cell to specific neuron type in forebrain [IMP]
- enteric nervous system development [TAS]
- forebrain neuron differentiation [ISO]
- generation of neurons [IMP]
- glial cell differentiation [IGI]
- lung neuroendocrine cell differentiation [IMP]
- musculoskeletal movement, spinal reflex action [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of neuron differentiation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- nervous system development [ISO]
- neuroblast fate determination [IMP]
- neuroblast proliferation [IGI]
- neurogenesis [IDA, ISO]
- neuron development [IMP]
- neuron differentiation [IGI, IMP]
- neuron fate commitment [IGI, IMP]
- neuron fate specification [IMP]
- neuron migration [IGI, IMP]
- noradrenergic neuron development [IMP]
- noradrenergic neuron fate commitment [ISO]
- olfactory pit development [IMP]
- oligodendrocyte cell fate commitment [IMP]
- oligodendrocyte development [IMP]
- oligodendrocyte differentiation [IMP]
- parasympathetic nervous system development [TAS]
- pattern specification process [IMP]
- positive regulation of Notch signaling pathway [IMP]
- positive regulation of cell cycle [IDA]
- positive regulation of neural precursor cell proliferation [IMP]
- positive regulation of neurogenesis [IMP]
- positive regulation of neuron apoptotic process [IMP]
- positive regulation of neuron differentiation [IDA, ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, ISO]
- regulation of Notch signaling pathway [IMP]
- regulation of cell proliferation [IDA]
- regulation of epithelial cell differentiation [IMP]
- regulation of gene expression [IMP]
- regulation of mitotic cell cycle [IMP]
- regulation of neurogenesis [IMP]
- regulation of timing of subpallium neuron differentiation [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA]
- spinal cord association neuron differentiation [IMP]
- spinal cord oligodendrocyte cell differentiation [IGI]
- spinal cord oligodendrocyte cell fate specification [IMP]
- stomach neuroendocrine cell differentiation [IMP]
- subpallium neuron fate commitment [IMP]
- sympathetic ganglion development [IMP]
- sympathetic nervous system development [TAS]
- transcription from RNA polymerase II promoter [ISO]
- ventral spinal cord interneuron fate commitment [IMP]
- vestibular nucleus development [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- E-box binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- bHLH transcription factor binding [ISO]
- chromatin binding [IDA]
- double-stranded DNA binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding transcription factor activity [IDA]
- DNA binding [IDA]
- E-box binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- bHLH transcription factor binding [ISO]
- chromatin binding [IDA]
- double-stranded DNA binding [ISO]
- protein binding [IPI]
- protein homodimerization activity [ISO]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding transcription factor activity [IDA]
Gene Ontology Cellular Component
Download Curated Data for this Protein
201314
10090
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- Interactors 9
- Interactions 18
- Network