Mus musculus
NKX2-2
Nkx-2.2, Nkx2.2, tinman, RP23-236O6.4
NK2 homeobox 2
GO Process (27)
GO Function (9)
GO Component (2)
Gene Ontology Biological Process
- astrocyte differentiation [IMP]
- cell development [IMP]
- cell differentiation [IMP]
- digestive tract development [IMP]
- endocrine pancreas development [IMP]
- negative regulation of neuron differentiation [IDA, IMP]
- nervous system development [IDA]
- neuron fate specification [IGI, IMP]
- oligodendrocyte development [IMP]
- pancreatic A cell fate commitment [IGI, IMP]
- pancreatic PP cell fate commitment [IGI]
- positive regulation of cell differentiation [IMP]
- positive regulation of gene expression [IDA]
- positive regulation of neuron differentiation [IDA, IMP]
- positive regulation of oligodendrocyte differentiation [IGI]
- positive regulation of sequence-specific DNA binding transcription factor activity [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of cell differentiation [IMP]
- regulation of transcription, DNA-templated [IDA]
- smoothened signaling pathway [IDA]
- spinal cord motor neuron differentiation [IMP]
- spinal cord oligodendrocyte cell differentiation [IGI, IMP]
- spinal cord oligodendrocyte cell fate specification [IDA]
- transcription from RNA polymerase II promoter [IDA]
- type B pancreatic cell development [IDA, IMP]
- type B pancreatic cell fate commitment [IMP]
- ventral spinal cord interneuron fate determination [IMP]
Gene Ontology Molecular Function- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [IDA]
- core promoter proximal region DNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IDA]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- chromatin binding [IDA]
- core promoter proximal region DNA binding [IDA]
- protein binding [IPI]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- transcription coactivator activity [IDA]
- transcription factor binding [IPI]
Gene Ontology Cellular Component
- intracellular [IDA]
- nucleus [IDA, ISO]
Download Curated Data for this Protein
201776
10090
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- Interactors 4
- Interactions 6
- Network