Mus musculus
PDGFRA
AI115593, CD140a, Pdgfr-2
platelet derived growth factor receptor, alpha polypeptide
GO Process (45)
GO Function (9)
GO Component (10)
Gene Ontology Biological Process
- Leydig cell differentiation [IMP]
- adrenal gland development [IGI]
- anatomical structure morphogenesis [IMP]
- cardiac myofibril assembly [IGI]
- cell chemotaxis [IMP, ISO]
- cell migration [IMP]
- cellular response to amino acid stimulus [IDA]
- cellular response to platelet-derived growth factor stimulus [IDA]
- embryonic cranial skeleton morphogenesis [IMP]
- embryonic digestive tract morphogenesis [IMP]
- estrogen metabolic process [IGI]
- extracellular matrix organization [IMP]
- face morphogenesis [IMP]
- female gonad development [IGI]
- hematopoietic progenitor cell differentiation [IMP]
- in utero embryonic development [IMP]
- lung development [IMP]
- luteinization [IGI, IMP]
- male genitalia development [IMP]
- metanephric glomerular capillary formation [IGI]
- negative regulation of platelet activation [ISO]
- odontogenesis of dentin-containing tooth [IMP]
- organ morphogenesis [IMP]
- palate development [IMP]
- peptidyl-tyrosine phosphorylation [IDA, ISO]
- phosphatidylinositol-mediated signaling [ISO]
- platelet aggregation [ISO]
- platelet-derived growth factor receptor signaling pathway [IMP, ISO]
- platelet-derived growth factor receptor-alpha signaling pathway [IDA, ISO]
- positive regulation of DNA replication [ISO]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway [ISO]
- positive regulation of cytosolic calcium ion concentration [ISO]
- positive regulation of fibroblast proliferation [ISO]
- positive regulation of phosphatidylinositol 3-kinase activity [ISO]
- positive regulation of phospholipase C activity [ISO]
- protein autophosphorylation [IDA, ISO]
- regulation of chemotaxis [ISO]
- regulation of mesenchymal stem cell differentiation [ISO]
- retina vasculature development in camera-type eye [IGI]
- signal transduction involved in regulation of gene expression [IDA]
- skeletal system morphogenesis [IMP]
- wound healing [IMP]
Gene Ontology Molecular Function- phosphatidylinositol 3-kinase binding [ISO]
- platelet-derived growth factor alpha-receptor activity [IDA, ISO]
- platelet-derived growth factor binding [IDA, ISO, TAS]
- platelet-derived growth factor receptor binding [ISO]
- protein complex binding [IDA]
- protein homodimerization activity [ISO]
- transmembrane receptor protein tyrosine kinase activity [ISO]
- vascular endothelial growth factor binding [ISO]
- vascular endothelial growth factor-activated receptor activity [ISO]
- phosphatidylinositol 3-kinase binding [ISO]
- platelet-derived growth factor alpha-receptor activity [IDA, ISO]
- platelet-derived growth factor binding [IDA, ISO, TAS]
- platelet-derived growth factor receptor binding [ISO]
- protein complex binding [IDA]
- protein homodimerization activity [ISO]
- transmembrane receptor protein tyrosine kinase activity [ISO]
- vascular endothelial growth factor binding [ISO]
- vascular endothelial growth factor-activated receptor activity [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
202088
10090
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- Interactors 6
- Interactions 7
- Network
- PTM Sites 1