Mus musculus
MED1
AI480703, CRSP210, DRIP205, PBP, Pparbp, TRAP220, l11Jus15, RP23-333M1.1
mediator complex subunit 1
GO Process (63)
GO Function (25)
GO Component (8)
Gene Ontology Biological Process
- ERK1 and ERK2 cascade [ISO]
- androgen biosynthetic process [ISO]
- androgen receptor signaling pathway [ISO]
- angiogenesis [IMP]
- brain development [IMP]
- camera-type eye development [IMP]
- cell morphogenesis [ISO]
- cellular response to epidermal growth factor stimulus [ISO]
- cellular response to hepatocyte growth factor stimulus [IMP]
- cellular response to steroid hormone stimulus [ISO]
- cellular response to thyroid hormone stimulus [ISO]
- embryonic heart tube development [IMP]
- embryonic hemopoiesis [IMP]
- embryonic hindlimb morphogenesis [IMP]
- embryonic placenta development [IMP]
- enucleate erythrocyte development [IMP]
- epithelial cell proliferation involved in mammary gland duct elongation [IMP]
- erythrocyte development [IMP]
- fat cell differentiation [IMP, ISO]
- heart development [IMP]
- in utero embryonic development [IMP]
- intracellular steroid hormone receptor signaling pathway [ISO]
- keratinocyte differentiation [ISO]
- lactation [IMP]
- lens development in camera-type eye [IMP]
- liver development [IMP]
- mRNA transcription from RNA polymerase II promoter [IMP]
- mammary gland branching involved in pregnancy [IMP]
- mammary gland branching involved in thelarche [IMP]
- mammary gland epithelial cell proliferation [IMP]
- megakaryocyte development [IMP]
- monocyte differentiation [IMP]
- multicellular organismal development [IMP]
- negative regulation of apoptotic process [IMP]
- negative regulation of keratinocyte proliferation [ISO]
- negative regulation of neuron differentiation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- organ morphogenesis [IMP]
- organ regeneration [IMP]
- peroxisome proliferator activated receptor signaling pathway [IMP]
- positive regulation of G0 to G1 transition [IMP]
- positive regulation of cell proliferation [IMP]
- positive regulation of gene expression [ISO]
- positive regulation of hepatocyte proliferation [IMP]
- positive regulation of interferon-gamma-mediated signaling pathway [IMP]
- positive regulation of intracellular estrogen receptor signaling pathway [IMP]
- positive regulation of keratinocyte differentiation [ISO]
- positive regulation of mammary gland epithelial cell proliferation [IMP]
- positive regulation of protein import into nucleus, translocation [IMP]
- positive regulation of receptor activity [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IMP, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- protein ubiquitination [ISO]
- regulation of RNA biosynthetic process [ISO]
- regulation of transcription from RNA polymerase I promoter [ISO]
- regulation of transcription, DNA-templated [IDA, IMP, TAS]
- regulation of vitamin D receptor signaling pathway [IMP]
- retinal pigment epithelium development [IMP]
- thyroid hormone generation [IMP]
- thyroid hormone mediated signaling pathway [ISO]
- transcription from RNA polymerase II promoter [IC]
- transcription initiation from RNA polymerase II promoter [ISO]
- ventricular trabecula myocardium morphogenesis [IMP]
Gene Ontology Molecular Function- DNA binding [IDA]
- LBD domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription cofactor activity [ISO]
- chromatin DNA binding [ISO]
- chromatin binding [IDA, ISO]
- core promoter binding [IDA, ISO]
- estrogen receptor binding [ISO]
- ligand-dependent nuclear receptor binding [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- mediator complex binding [ISO]
- nuclear hormone receptor binding [IPI, ISO]
- peroxisome proliferator activated receptor binding [ISO]
- protein binding [IPI]
- protein complex binding [IDA, ISO]
- receptor activity [ISO]
- retinoic acid receptor binding [ISO]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IMP]
- thyroid hormone receptor binding [ISO]
- thyroid hormone receptor coactivator activity [ISO]
- transcription coactivator activity [IDA, ISO, TAS]
- transcription cofactor activity [ISO]
- transcription factor binding [IPI, ISO]
- ubiquitin protein ligase activity [ISO]
- vitamin D receptor binding [ISO]
- DNA binding [IDA]
- LBD domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription cofactor activity [ISO]
- chromatin DNA binding [ISO]
- chromatin binding [IDA, ISO]
- core promoter binding [IDA, ISO]
- estrogen receptor binding [ISO]
- ligand-dependent nuclear receptor binding [ISO]
- ligand-dependent nuclear receptor transcription coactivator activity [ISO]
- mediator complex binding [ISO]
- nuclear hormone receptor binding [IPI, ISO]
- peroxisome proliferator activated receptor binding [ISO]
- protein binding [IPI]
- protein complex binding [IDA, ISO]
- receptor activity [ISO]
- retinoic acid receptor binding [ISO]
- sequence-specific DNA binding RNA polymerase II transcription factor activity [IMP]
- thyroid hormone receptor binding [ISO]
- thyroid hormone receptor coactivator activity [ISO]
- transcription coactivator activity [IDA, ISO, TAS]
- transcription cofactor activity [ISO]
- transcription factor binding [IPI, ISO]
- ubiquitin protein ligase activity [ISO]
- vitamin D receptor binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
202318
10090
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- Interactors 14
- Interactions 17
- Network