Mus musculus
TCF3
A1, AA408400, ALF2, AW209082, E12, E12/E47, E2A, E47, ME2, Pan1, Pan2, TCF-3, Tcfe2a, VDIR, bHLHb21
transcription factor 3
GO Process (26)
GO Function (21)
GO Component (8)
Gene Ontology Biological Process
- B cell lineage commitment [ISO]
- Peyer's patch development [IGI]
- T cell differentiation in thymus [IMP]
- cell development [IGI]
- gastrulation [IGI]
- histone H3 acetylation [IMP]
- histone H4 acetylation [IMP]
- immunoglobulin V(D)J recombination [IMP, ISO]
- lymphocyte differentiation [IMP]
- natural killer cell differentiation [IGI]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of B cell proliferation [ISO]
- positive regulation of cell cycle [ISO]
- positive regulation of gene expression [IMP, ISO]
- positive regulation of neuron differentiation [IDA]
- positive regulation of sequence-specific DNA binding transcription factor activity [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA, IGI, IMP, ISO]
- positive regulation of transcription, DNA-templated [IDA, IGI, ISO]
- protein stabilization [IDA]
- regulation of G1/S transition of mitotic cell cycle [ISO]
- regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of transcription, DNA-templated [IDA, IGI, TAS]
- response to drug [IMP]
- response to lipopolysaccharide [IMP]
- transcription from RNA polymerase II promoter [IMP]
- transcription, DNA-templated [ISO]
Gene Ontology Molecular Function- DNA binding [IDA, ISO]
- E-box binding [IDA, ISO]
- PDZ domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, IMP, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IMP]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IMP]
- bHLH transcription factor binding [ISO]
- chromatin binding [IDA]
- mitogen-activated protein kinase kinase kinase binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding [IDA, IGI, ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription coactivator activity [ISO]
- transcription factor binding [IPI, ISO]
- transcription regulatory region DNA binding [ISO]
- vitamin D response element binding [ISO]
- DNA binding [IDA, ISO]
- E-box binding [IDA, ISO]
- PDZ domain binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA, IMP, ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA, IMP]
- RNA polymerase II distal enhancer sequence-specific DNA binding [IMP]
- RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IMP]
- bHLH transcription factor binding [ISO]
- chromatin binding [IDA]
- mitogen-activated protein kinase kinase kinase binding [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IDA, IPI, ISO]
- protein homodimerization activity [IDA, ISO]
- repressing transcription factor binding [ISO]
- sequence-specific DNA binding [IDA, IGI, ISO]
- sequence-specific DNA binding transcription factor activity [ISO, TAS]
- transcription coactivator activity [ISO]
- transcription factor binding [IPI, ISO]
- transcription regulatory region DNA binding [ISO]
- vitamin D response element binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
204015
10090
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- Interactors 103
- Interactions 126
- Network
- PTM Sites 7