Mus musculus
TRP73
TAp73, Tp73, deltaNp73, p73, RP23-254N4.10-001
transformation related protein 73
GO Process (33)
GO Function (14)
GO Component (9)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator [IBA]
- activation of MAPK activity [ISO]
- cell cycle arrest [IDA]
- cellular response to DNA damage stimulus [IMP, ISO]
- cellular response to UV [IBA]
- cerebrospinal fluid secretion [IMP]
- digestive tract morphogenesis [IMP]
- forebrain development [IMP]
- hippocampus development [IMP]
- inflammatory response [IMP]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IBA, ISO]
- mitotic G1 DNA damage checkpoint [IBA]
- negative regulation of JUN kinase activity [IDA]
- negative regulation of cardiac muscle cell proliferation [ISO]
- negative regulation of neuron apoptotic process [IDA, IMP]
- negative regulation of neuron differentiation [ISO]
- negative regulation of transcription from RNA polymerase II promoter [IBA]
- neuron development [IMP]
- positive regulation of apoptotic process [ISO]
- positive regulation of apoptotic signaling pathway [IGI]
- positive regulation of cell size [IMP]
- positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [IGI]
- positive regulation of oligodendrocyte differentiation [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IBA, ISO]
- positive regulation of transcription, DNA-templated [IDA, ISO]
- post-embryonic development [IMP]
- regulation of gene expression [ISO]
- regulation of mitotic cell cycle [ISO]
- regulation of neuron apoptotic process [IGI]
- release of cytochrome c from mitochondria [IDA]
- response to X-ray [IBA]
- response to gamma radiation [IBA]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- chromatin binding [IBA]
- damaged DNA binding [IBA]
- double-stranded DNA binding [IBA]
- identical protein binding [ISO]
- p53 binding [IPI]
- protein binding [IPI]
- protein kinase binding [ISO]
- sequence-specific DNA binding [IBA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [ISO]
- chromatin binding [IBA]
- damaged DNA binding [IBA]
- double-stranded DNA binding [IBA]
- identical protein binding [ISO]
- p53 binding [IPI]
- protein binding [IPI]
- protein kinase binding [ISO]
- sequence-specific DNA binding [IBA, ISO]
- sequence-specific DNA binding transcription factor activity [IDA, ISO]
- transcription factor binding [ISO]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
204326
10090
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- Interactors 5
- Interactions 6
- Network