Mus musculus
PINK1
1190006F07Rik, AU042772, AW557854, BRPK, mFLJ00387
PTEN induced putative kinase 1
GO Process (28)
GO Function (9)
GO Component (16)
Gene Ontology Biological Process
- cellular response to hypoxia [ISO]
- cellular response to toxic substance [IMP]
- intracellular signal transduction [IDA, ISO]
- mitochondrion degradation [IBA, ISO]
- mitochondrion organization [ISO]
- negative regulation of gene expression [ISO]
- negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway [ISO]
- negative regulation of neuron apoptotic process [IMP, ISO]
- negative regulation of oxidative stress-induced cell death [ISO]
- negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [ISO]
- negative regulation of reactive oxygen species metabolic process [ISO]
- peptidyl-serine phosphorylation [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of catecholamine secretion [IMP]
- positive regulation of dopamine secretion [IMP]
- positive regulation of mitochondrial fission [IBA]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of release of cytochrome c from mitochondria [ISO]
- positive regulation of synaptic transmission, dopaminergic [IMP]
- protein phosphorylation [IDA, IMP, ISO]
- protein ubiquitination [ISO]
- regulation of mitochondrial membrane potential [ISO]
- regulation of neuron apoptotic process [IMP]
- regulation of protein complex assembly [ISO]
- regulation of protein ubiquitination [ISO]
- regulation of reactive oxygen species metabolic process [ISO]
- response to oxidative stress [ISO]
- response to stress [ISO]
Gene Ontology Molecular Function- ATP binding [IDA, ISO]
- C3HC4-type RING finger domain binding [ISO]
- calcium-dependent protein kinase activity [ISO]
- kinase activity [IDA, ISO]
- magnesium ion binding [IDA, ISO]
- protease binding [ISO]
- protein kinase B binding [ISO]
- protein serine/threonine kinase activity [IDA, IMP, ISO]
- ubiquitin protein ligase binding [ISO]
- ATP binding [IDA, ISO]
- C3HC4-type RING finger domain binding [ISO]
- calcium-dependent protein kinase activity [ISO]
- kinase activity [IDA, ISO]
- magnesium ion binding [IDA, ISO]
- protease binding [ISO]
- protein kinase B binding [ISO]
- protein serine/threonine kinase activity [IDA, IMP, ISO]
- ubiquitin protein ligase binding [ISO]
Gene Ontology Cellular Component
- TORC2 complex [ISO]
- astrocyte projection [ISO]
- axon [ISO]
- cell body [ISO]
- chromatin [ISO]
- cytoplasm [ISO]
- cytoskeleton [ISO]
- cytosol [ISO]
- integral component of mitochondrial outer membrane [ISO]
- membrane [ISO]
- mitochondrial inner membrane [ISO]
- mitochondrial intermembrane space [ISO]
- mitochondrial outer membrane [ISO]
- mitochondrion [IDA, ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
Download Curated Data for this Protein
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- Interactors 2
- Interactions 2
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