Mus musculus
TIRAP
AA407980, C130027E04Rik, Mal, Tlr4ap, Wyatt
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
GO Process (35)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- 3'-UTR-mediated mRNA stabilization [ISO]
- I-kappaB kinase/NF-kappaB signaling [IMP, ISO]
- TIRAP-dependent toll-like receptor 4 signaling pathway [ISO]
- activation of JUN kinase activity [ISO]
- cell surface receptor signaling pathway [IPI, ISO]
- cellular response to bacterial lipopeptide [IMP]
- cellular response to lipoteichoic acid [IMP]
- defense response to Gram-positive bacterium [IMP]
- interleukin-1-mediated signaling pathway [IDA, NAS]
- myeloid cell differentiation [IMP]
- negative regulation of growth of symbiont in host [IMP]
- positive regulation of B cell proliferation [IMP]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of I-kappaB kinase/NF-kappaB signaling [ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of NF-kappaB transcription factor activity [IMP, ISO]
- positive regulation of chemokine (C-X-C motif) ligand 1 production [IMP]
- positive regulation of chemokine (C-X-C motif) ligand 2 production [IMP]
- positive regulation of innate immune response [IMP]
- positive regulation of interleukin-12 production [IMP]
- positive regulation of interleukin-15 production [ISO]
- positive regulation of interleukin-6 biosynthetic process [IDA, IMP, ISO]
- positive regulation of interleukin-8 production [IMP, ISO]
- positive regulation of neutrophil chemotaxis [IMP]
- positive regulation of protein homodimerization activity [ISO]
- positive regulation of toll-like receptor 2 signaling pathway [ISO]
- positive regulation of toll-like receptor 3 signaling pathway [IDA]
- positive regulation of toll-like receptor 4 signaling pathway [ISO]
- positive regulation of tumor necrosis factor production [IMP, ISO]
- regulation of innate immune response [NAS]
- regulation of interferon-beta production [IDA]
- regulation of interleukin-15 production [IMP]
- response to bacterium [ISO]
- response to lipopolysaccharide [ISO]
- toll-like receptor 5 signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Download Curated Data for this Protein
228172
10090
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- Interactors 11
- Interactions 13
- Network