Rattus norvegicus
                     DRD2
dopamine receptor D2
 
                     
                     
                     GO Process (99)
GO Function (11)
GO Component (15)
Gene Ontology Biological Process
- G-protein coupled receptor internalization [IDA]
 - G-protein coupled receptor signaling pathway [ISO]
 - Wnt signaling pathway [IDA]
 - acid secretion [IDA]
 - activation of protein kinase activity [IDA]
 - adenohypophysis development [ISO]
 - adenylate cyclase-inhibiting dopamine receptor signaling pathway [IDA, ISO]
 - adenylate cyclase-modulating G-protein coupled receptor signaling pathway [IDA]
 - adult behavior [ISO]
 - adult walking behavior [ISO]
 - arachidonic acid secretion [ISO]
 - associative learning [ISO]
 - auditory behavior [IMP]
 - axonogenesis [ISO]
 - behavioral response to cocaine [ISO]
 - behavioral response to ethanol [ISO]
 - branching morphogenesis of a nerve [ISO]
 - cellular potassium ion homeostasis [IC]
 - cerebral cortex GABAergic interneuron migration [ISO]
 - circadian regulation of gene expression [ISO]
 - dopamine metabolic process [ISO]
 - dopamine receptor signaling pathway [IDA, IMP, ISO, TAS]
 - feeding behavior [ISO]
 - forebrain development [IMP]
 - grooming behavior [ISO]
 - intracellular signal transduction [ISO]
 - locomotory behavior [IMP, ISO]
 - long-term memory [IMP]
 - negative regulation of adenylate cyclase activity [IDA, ISO]
 - negative regulation of blood pressure [ISO]
 - negative regulation of cell migration [ISO]
 - negative regulation of cell proliferation [ISO]
 - negative regulation of circadian sleep/wake cycle, sleep [IDA]
 - negative regulation of cytosolic calcium ion concentration [IMP]
 - negative regulation of dopamine receptor signaling pathway [ISO]
 - negative regulation of dopamine secretion [IMP]
 - negative regulation of insulin secretion [IMP]
 - negative regulation of protein kinase B signaling [ISO]
 - negative regulation of protein secretion [ISO]
 - negative regulation of synaptic transmission, glutamatergic [ISO]
 - negative regulation of voltage-gated calcium channel activity [IDA, ISO]
 - neurological system process involved in regulation of systemic arterial blood pressure [ISO]
 - neuron-neuron synaptic transmission [ISO]
 - orbitofrontal cortex development [IEP]
 - peristalsis [ISO]
 - phosphatidylinositol metabolic process [IDA]
 - phospholipase C-activating dopamine receptor signaling pathway [ISO]
 - pigmentation [ISO]
 - positive regulation of ERK1 and ERK2 cascade [IMP]
 - positive regulation of G-protein coupled receptor protein signaling pathway [IMP]
 - positive regulation of cytokinesis [ISO]
 - positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway [ISO]
 - positive regulation of dopamine uptake involved in synaptic transmission [ISO]
 - positive regulation of growth hormone secretion [ISO]
 - positive regulation of long-term synaptic potentiation [IMP]
 - positive regulation of mitosis [TAS]
 - positive regulation of multicellular organism growth [ISO]
 - positive regulation of neuroblast proliferation [ISO]
 - positive regulation of receptor internalization [IMP]
 - positive regulation of renal sodium excretion [ISO]
 - positive regulation of transcription from RNA polymerase II promoter [IDA]
 - positive regulation of urine volume [ISO]
 - prepulse inhibition [ISO]
 - protein localization [ISO]
 - regulation of MAPK cascade [IDA]
 - regulation of cAMP metabolic process [ISO]
 - regulation of dopamine secretion [ISO]
 - regulation of dopamine uptake involved in synaptic transmission [ISO]
 - regulation of heart rate [ISO]
 - regulation of locomotion involved in locomotory behavior [IMP]
 - regulation of long-term neuronal synaptic plasticity [ISO]
 - regulation of phosphoprotein phosphatase activity [IMP]
 - regulation of potassium ion transport [IDA, ISO]
 - regulation of sodium ion transport [ISO]
 - regulation of synapse structural plasticity [IDA]
 - regulation of synaptic transmission [IDA, ISO]
 - regulation of synaptic transmission, GABAergic [ISO]
 - release of sequestered calcium ion into cytosol [IMP]
 - response to amphetamine [IEP, ISO]
 - response to axon injury [IEP]
 - response to cocaine [ISO]
 - response to drug [IDA, ISO]
 - response to ethanol [IEP]
 - response to histamine [ISO]
 - response to hypoxia [IMP]
 - response to inactivity [IEP]
 - response to iron ion [IEP]
 - response to light stimulus [ISO]
 - response to morphine [ISO]
 - response to nicotine [IEP]
 - response to toxic substance [IEP]
 - sensory perception of smell [ISO]
 - startle response [ISO]
 - striatum development [IEP]
 - synapse assembly [IEP]
 - synaptic transmission [ISO]
 - synaptic transmission, dopaminergic [IDA, IMP]
 - temperature homeostasis [ISO]
 - visual learning [ISO]
 
Gene Ontology Molecular Function- G-protein coupled receptor activity [ISO]
 - dopamine binding [IMP, ISO]
 - dopamine neurotransmitter receptor activity [IMP, ISO]
 - dopamine neurotransmitter receptor activity, coupled via Gi/Go [IDA, ISO]
 - drug binding [IDA, ISO]
 - identical protein binding [ISO]
 - ionotropic glutamate receptor binding [IPI]
 - protein binding [IPI]
 - protein heterodimerization activity [IPI]
 - protein homodimerization activity [IDA]
 - receptor binding [IPI]
 
- G-protein coupled receptor activity [ISO]
 - dopamine binding [IMP, ISO]
 - dopamine neurotransmitter receptor activity [IMP, ISO]
 - dopamine neurotransmitter receptor activity, coupled via Gi/Go [IDA, ISO]
 - drug binding [IDA, ISO]
 - identical protein binding [ISO]
 - ionotropic glutamate receptor binding [IPI]
 - protein binding [IPI]
 - protein heterodimerization activity [IPI]
 - protein homodimerization activity [IDA]
 - receptor binding [IPI]
 
Gene Ontology Cellular Component
- acrosomal vesicle [IDA]
 - axon [IDA, ISO]
 - axon terminus [IDA]
 - cytoplasmic vesicle [IDA]
 - dendrite [IDA, ISO]
 - dendritic spine [IDA]
 - endocytic vesicle [IDA]
 - integral component of plasma membrane [ISO]
 - lateral plasma membrane [IDA]
 - membrane [IDA, ISO]
 - perikaryon [IDA]
 - plasma membrane [IDA]
 - postsynaptic density [IDA]
 - sperm flagellum [IDA]
 - synaptic vesicle membrane [IDA]
 
 Download Curated Data for this Protein
 
                     246498
                     10116
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                         - Interactors 11
 - Interactions 13
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