Rattus norvegicus
EGFR
ERBB1, ErbB-1, Errp
epidermal growth factor receptor
GO Process (72)
GO Function (19)
GO Component (15)
Gene Ontology Biological Process
- activation of MAPKK activity [IMP]
- astrocyte activation [IMP]
- cell morphogenesis [ISO]
- cell proliferation [ISO]
- cell surface receptor signaling pathway [ISO]
- cellular response to amino acid stimulus [ISO]
- cellular response to dexamethasone stimulus [IEP]
- cellular response to drug [IEP]
- cellular response to epidermal growth factor stimulus [IDA]
- cellular response to estradiol stimulus [ISO]
- cellular response to growth factor stimulus [IEP]
- cellular response to mechanical stimulus [IEP]
- cerebral cortex cell migration [ISO]
- circadian rhythm [IEP]
- digestive tract morphogenesis [ISO]
- diterpenoid metabolic process [IEP]
- embryonic placenta development [ISO]
- epidermal growth factor receptor signaling pathway [IDA, IMP, ISO]
- epidermis development [ISO]
- hair follicle development [ISO]
- hydrogen peroxide metabolic process [IEP]
- intracellular signal transduction [IDA]
- learning or memory [IDA]
- liver development [IEP]
- lung development [IEP]
- magnesium ion homeostasis [IMP]
- morphogenesis of an epithelial fold [ISO]
- negative regulation of apoptotic process [IMP, ISO]
- negative regulation of mitotic cell cycle [IMP]
- negative regulation of protein catabolic process [ISO]
- neuron projection morphogenesis [IMP]
- ovulation cycle [IMP]
- peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of DNA repair [ISO]
- positive regulation of DNA replication [ISO]
- positive regulation of ERK1 and ERK2 cascade [ISO]
- positive regulation of MAP kinase activity [ISO]
- positive regulation of catenin import into nucleus [ISO]
- positive regulation of cell migration [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle [ISO]
- positive regulation of epithelial cell proliferation [ISO]
- positive regulation of fibroblast proliferation [ISO]
- positive regulation of inflammatory response [IMP]
- positive regulation of nitric oxide biosynthetic process [ISO]
- positive regulation of phosphorylation [ISO]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of protein phosphorylation [ISO]
- positive regulation of smooth muscle cell proliferation [IMP]
- positive regulation of superoxide anion generation [IMP]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of vasoconstriction [IMP]
- positive regulation of vasodilation [IMP]
- protein autophosphorylation [IDA, ISO]
- regulation of cell proliferation [ISO]
- regulation of nitric-oxide synthase activity [ISO]
- regulation of peptidyl-tyrosine phosphorylation [ISO]
- response to UV-A [ISO]
- response to calcium ion [IMP]
- response to cobalamin [IEP]
- response to estradiol [IEP]
- response to hydroxyisoflavone [IEP]
- response to lipid [IEP]
- response to organic cyclic compound [IEP]
- response to osmotic stress [IEP]
- response to oxidative stress [IEP]
- salivary gland morphogenesis [ISO]
- signal transduction [IDA, ISO]
- single organismal cell-cell adhesion [ISO]
- tongue development [IEP]
- translation [IDA]
Gene Ontology Molecular Function- actin filament binding [ISO]
- chromatin binding [ISO]
- enzyme binding [ISO]
- epidermal growth factor binding [IMP]
- epidermal growth factor-activated receptor activity [IDA, IMP, ISO, TAS]
- glycoprotein binding [IPI]
- identical protein binding [ISO]
- integrin binding [IPI]
- kinase activity [ISO]
- nitric-oxide synthase regulator activity [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein kinase binding [IPI]
- protein phosphatase binding [ISO]
- protein tyrosine kinase activity [ISO]
- receptor binding [IPI]
- signal transducer activity [ISO]
- transmembrane signaling receptor activity [ISO]
- ubiquitin protein ligase binding [ISO]
- actin filament binding [ISO]
- chromatin binding [ISO]
- enzyme binding [ISO]
- epidermal growth factor binding [IMP]
- epidermal growth factor-activated receptor activity [IDA, IMP, ISO, TAS]
- glycoprotein binding [IPI]
- identical protein binding [ISO]
- integrin binding [IPI]
- kinase activity [ISO]
- nitric-oxide synthase regulator activity [ISO]
- protein binding [IPI]
- protein heterodimerization activity [IPI, ISO]
- protein kinase binding [IPI]
- protein phosphatase binding [ISO]
- protein tyrosine kinase activity [ISO]
- receptor binding [IPI]
- signal transducer activity [ISO]
- transmembrane signaling receptor activity [ISO]
- ubiquitin protein ligase binding [ISO]
Gene Ontology Cellular Component
- apical plasma membrane [IDA]
- basolateral plasma membrane [IDA, ISO]
- cell surface [IDA]
- cytoplasm [ISO]
- endocytic vesicle [IDA, ISO]
- endosome [IDA, ISO]
- endosome membrane [ISO]
- focal adhesion [ISO]
- intracellular [ISO]
- membrane [ISO]
- membrane raft [ISO]
- nucleus [IDA, ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [IDA, ISO]
- receptor complex [ISO]
Download Curated Data for this Protein
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- Interactors 13
- Interactions 17
- Network