Rattus norvegicus
PDE4D
phosphodiesterase 4D, cAMP-specific
GO Process (31)
GO Function (14)
GO Component (8)
Gene Ontology Biological Process
- T cell receptor signaling pathway [ISO]
- adrenergic receptor signaling pathway [IMP]
- adrenergic receptor signaling pathway involved in positive regulation of heart rate [IC]
- aging [ISO]
- cAMP catabolic process [IDA, IMP, ISO]
- cellular protein complex assembly [IDA]
- cellular response to cAMP [ISO]
- cellular response to epinephrine stimulus [ISO]
- cellular response to lipopolysaccharide [ISO]
- establishment of endothelial barrier [IDA]
- leukocyte migration [ISO]
- lung development [IEP]
- memory [IEP, IMP]
- multicellular organism growth [ISO]
- negative regulation of heart contraction [ISO]
- negative regulation of peptidyl-serine phosphorylation [ISO]
- negative regulation of relaxation of cardiac muscle [ISO]
- neutrophil chemotaxis [ISO]
- positive regulation of interferon-gamma production [ISO]
- positive regulation of interleukin-2 production [ISO]
- positive regulation of interleukin-5 production [ISO]
- positive regulation of smooth muscle cell migration [IMP]
- positive regulation of smooth muscle cell proliferation [IMP]
- regulation of G-protein coupled receptor protein signaling pathway [IDA]
- regulation of cardiac muscle cell contraction [IMP, ISO]
- regulation of heart rate [ISO]
- regulation of protein kinase A signaling [IMP]
- regulation of receptor activity [IMP]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [ISO]
- regulation of ryanodine-sensitive calcium-release channel activity [ISO]
- smooth muscle contraction [ISO]
Gene Ontology Molecular Function- 3',5'-cyclic-AMP phosphodiesterase activity [IDA, IMP, ISO]
- 3',5'-cyclic-nucleotide phosphodiesterase activity [ISO]
- ATPase binding [ISO]
- SH3 domain binding [IPI]
- beta-2 adrenergic receptor binding [IPI]
- cAMP binding [IMP, ISO]
- cyclic-nucleotide phosphodiesterase activity [IDA]
- drug binding [ISO]
- enzyme binding [IPI]
- ion channel binding [ISO]
- protein binding [IPI]
- protein domain specific binding [IPI]
- scaffold protein binding [ISO]
- ubiquitin protein ligase binding [ISO]
- 3',5'-cyclic-AMP phosphodiesterase activity [IDA, IMP, ISO]
- 3',5'-cyclic-nucleotide phosphodiesterase activity [ISO]
- ATPase binding [ISO]
- SH3 domain binding [IPI]
- beta-2 adrenergic receptor binding [IPI]
- cAMP binding [IMP, ISO]
- cyclic-nucleotide phosphodiesterase activity [IDA]
- drug binding [ISO]
- enzyme binding [IPI]
- ion channel binding [ISO]
- protein binding [IPI]
- protein domain specific binding [IPI]
- scaffold protein binding [ISO]
- ubiquitin protein ligase binding [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
246765
10116
Switch View:
- Interactors 5
- Interactions 5
- Network
- PTM Sites 1