Rattus norvegicus
TAP2
Abcb3, Cim
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
GO Process (14)
GO Function (15)
GO Component (6)
Gene Ontology Biological Process
- antigen processing and presentation of endogenous peptide antigen via MHC class I [IDA, ISO]
- antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent [IBA, ISO]
- antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent [IBA, ISO]
- antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent [IBA, ISO]
- cytosol to ER transport [ISO]
- intracellular transport of viral protein in host cell [ISO]
- peptide antigen transport [ISO, TAS]
- peptide transport [IMP]
- positive regulation of T cell mediated cytotoxicity [IDA, ISO]
- positive regulation of antigen processing and presentation of peptide antigen via MHC class I [IMP]
- protection from natural killer cell mediated cytotoxicity [IMP]
- protein complex assembly [IDA]
- response to molecule of bacterial origin [ISO]
- transmembrane transport [IBA]
Gene Ontology Molecular Function- ADP binding [IDA]
- ATP binding [IDA, IMP, ISO]
- ATPase activity, coupled to transmembrane movement of substances [IBA]
- MHC class I protein binding [IDA]
- MHC class Ib protein binding [ISO]
- TAP1 binding [IPI, ISO]
- TAP2 binding [IPI]
- nucleotide binding [IDA]
- peptide antigen binding [IDA]
- peptide antigen-transporting ATPase activity [ISO, TAS]
- peptide transporter activity [ISO]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA, IPI]
- tapasin binding [IDA, IPI]
- transporter activity [ISO]
- ADP binding [IDA]
- ATP binding [IDA, IMP, ISO]
- ATPase activity, coupled to transmembrane movement of substances [IBA]
- MHC class I protein binding [IDA]
- MHC class Ib protein binding [ISO]
- TAP1 binding [IPI, ISO]
- TAP2 binding [IPI]
- nucleotide binding [IDA]
- peptide antigen binding [IDA]
- peptide antigen-transporting ATPase activity [ISO, TAS]
- peptide transporter activity [ISO]
- protein heterodimerization activity [IDA]
- protein homodimerization activity [IDA, IPI]
- tapasin binding [IDA, IPI]
- transporter activity [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
246934
10116
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- Interactors 7
- Interactions 9
- Network