Rattus norvegicus
SYK
p72syk
spleen tyrosine kinase
GO Process (53)
GO Function (11)
GO Component (10)
Gene Ontology Biological Process
- B cell receptor signaling pathway [IBA, ISO, ISS]
- activation of JUN kinase activity [ISO]
- activation of MAPK activity [ISO]
- adaptive immune response [IBA, ISS]
- beta selection [ISO]
- blood vessel morphogenesis [ISO, ISS]
- cell migration [IBA]
- cell surface receptor signaling pathway [ISO]
- cellular response to molecule of fungal origin [ISO, ISS]
- defense response to bacterium [ISO, ISS]
- enzyme linked receptor protein signaling pathway [ISO]
- inflammatory response [IBA]
- innate immune response [IBA, ISO, ISS]
- integrin-mediated signaling pathway [ISO, ISS]
- intracellular signal transduction [ISO]
- leukocyte activation involved in immune response [ISO, ISS]
- leukocyte cell-cell adhesion [ISO, ISS]
- leukotriene biosynthetic process [ISO]
- lymph vessel development [ISO, ISS]
- macrophage activation involved in immune response [IBA, ISO, ISS]
- neutrophil activation involved in immune response [IBA, ISO, ISS]
- neutrophil chemotaxis [ISO, ISS]
- peptidyl-serine phosphorylation [ISO]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of B cell differentiation [IBA, ISO]
- positive regulation of alpha-beta T cell differentiation [ISO]
- positive regulation of alpha-beta T cell proliferation [IBA, ISO]
- positive regulation of bone resorption [ISO, ISS]
- positive regulation of calcium-mediated signaling [ISO]
- positive regulation of cell adhesion mediated by integrin [IBA, ISO, ISS]
- positive regulation of cytokine secretion [ISO]
- positive regulation of gamma-delta T cell differentiation [ISO]
- positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process [ISO]
- positive regulation of interleukin-3 biosynthetic process [ISO]
- positive regulation of mast cell degranulation [IMP, ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [ISO]
- protein autophosphorylation [IDA, ISO]
- protein phosphorylation [ISS]
- regulation of ERK1 and ERK2 cascade [ISO, ISS]
- regulation of arachidonic acid secretion [ISO, ISS]
- regulation of immune response [IDA]
- regulation of neutrophil degranulation [ISO, ISS]
- regulation of phagocytosis [ISO, ISS]
- regulation of platelet activation [ISO, ISS]
- regulation of platelet aggregation [IBA, ISO, ISS]
- regulation of sequence-specific DNA binding transcription factor activity [ISO]
- regulation of superoxide anion generation [ISO, ISS]
- serotonin secretion [ISO]
- serotonin secretion by platelet [ISO, ISS]
- signal transduction by phosphorylation [ISO]
- transcription factor import into nucleus [ISO]
- transmembrane receptor protein tyrosine kinase signaling pathway [IBA]
Gene Ontology Molecular Function- ATP binding [ISO]
- integrin binding [ISO]
- non-membrane spanning protein tyrosine kinase activity [IBA, ISO, ISS]
- protein binding [IPI]
- protein domain specific binding [IMP]
- protein kinase activity [IDA]
- protein kinase binding [ISO]
- protein serine/threonine kinase activity [ISO]
- protein tyrosine kinase activity [ISO]
- receptor binding [IBA]
- receptor signaling protein tyrosine kinase activity [ISO]
- ATP binding [ISO]
- integrin binding [ISO]
- non-membrane spanning protein tyrosine kinase activity [IBA, ISO, ISS]
- protein binding [IPI]
- protein domain specific binding [IMP]
- protein kinase activity [IDA]
- protein kinase binding [ISO]
- protein serine/threonine kinase activity [ISO]
- protein tyrosine kinase activity [ISO]
- receptor binding [IBA]
- receptor signaling protein tyrosine kinase activity [ISO]
Gene Ontology Cellular Component
Download Curated Data for this Protein
247220
10116
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- Interactors 2
- Interactions 2
- Network