Rattus norvegicus
NPM1
B23NP
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
GO Process (38)
GO Function (17)
GO Component (16)
Gene Ontology Biological Process
- DNA repair [ISO, ISS]
- cell aging [ISO, ISS]
- cell growth [ISO]
- cell volume homeostasis [ISO]
- centrosome cycle [ISO, ISS]
- negative regulation of apoptotic process [ISO, ISS]
- negative regulation of cell proliferation [ISO, ISS]
- negative regulation of centrosome duplication [ISO]
- negative regulation of mRNA splicing, via spliceosome [ISO]
- negative regulation of protein kinase activity by regulation of protein phosphorylation [ISO, ISS]
- nucleocytoplasmic transport [ISO]
- nucleosome assembly [ISO]
- positive regulation of DNA metabolic process [IDA]
- positive regulation of DNA replication [IDA]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of catalytic activity [IDA]
- positive regulation of cell proliferation [ISO]
- positive regulation of cellular biosynthetic process [ISO]
- positive regulation of centrosome duplication [ISO]
- positive regulation of protein kinase activity [ISO]
- positive regulation of translation [ISO, ISS]
- protein destabilization [ISO]
- protein homooligomerization [IDA]
- protein localization [ISO]
- protein oligomerization [ISO]
- rRNA export from nucleus [ISO]
- regulation of DNA damage response, signal transduction by p53 class mediator [ISO]
- regulation of cell cycle [ISO]
- regulation of centriole replication [ISO, ISS]
- regulation of centrosome duplication [ISO]
- regulation of eIF2 alpha phosphorylation by dsRNA [ISO, ISS]
- regulation of endodeoxyribonuclease activity [ISO, ISS]
- regulation of endoribonuclease activity [ISO, ISS]
- regulation of neuron apoptotic process [IMP]
- ribosomal large subunit biogenesis [ISO]
- ribosomal large subunit export from nucleus [ISO]
- ribosomal small subunit biogenesis [ISO]
- ribosomal small subunit export from nucleus [ISO]
Gene Ontology Molecular Function- DNA binding [IDA]
- NF-kappaB binding [ISO, ISS]
- RNA binding [ISO]
- Tat protein binding [ISO]
- enzyme binding [IDA, IPI]
- histone binding [ISO]
- phosphatidylinositol-3,4,5-trisphosphate binding [IPI]
- poly(A) RNA binding [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
- protein kinase inhibitor activity [ISO, ISS]
- rRNA binding [ISO]
- ribosomal large subunit binding [ISO]
- ribosomal small subunit binding [ISO]
- transcription coactivator activity [ISO]
- unfolded protein binding [ISO, ISS]
- DNA binding [IDA]
- NF-kappaB binding [ISO, ISS]
- RNA binding [ISO]
- Tat protein binding [ISO]
- enzyme binding [IDA, IPI]
- histone binding [ISO]
- phosphatidylinositol-3,4,5-trisphosphate binding [IPI]
- poly(A) RNA binding [ISO]
- protein heterodimerization activity [ISO]
- protein homodimerization activity [ISO]
- protein kinase binding [ISO]
- protein kinase inhibitor activity [ISO, ISS]
- rRNA binding [ISO]
- ribosomal large subunit binding [ISO]
- ribosomal small subunit binding [ISO]
- transcription coactivator activity [ISO]
- unfolded protein binding [ISO, ISS]
Gene Ontology Cellular Component
- cell [ISO]
- centrosome [ISO, ISS]
- cytoplasm [ISO, ISS]
- cytosol [ISO]
- focal adhesion [ISO]
- granular component [ISO]
- intracellular [ISO]
- large ribosomal subunit [ISO]
- membrane [ISO]
- nuclear speck [ISO]
- nucleolus [IDA, ISO]
- nucleoplasm [ISO]
- nucleus [ISO, ISS]
- ribonucleoprotein complex [ISO]
- small ribosomal subunit [ISO]
- spindle pole centrosome [ISO]
Download Curated Data for this Protein
247531
10116
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- Interactors 7
- Interactions 7
- Network