Rattus norvegicus
LEP
OB, obese
leptin
GO Process (68)
GO Function (4)
GO Component (3)
Gene Ontology Biological Process
- JAK-STAT cascade [TAS]
- adipose tissue development [ISO]
- adult feeding behavior [ISO, ISS]
- bile acid metabolic process [ISO]
- bone mineralization involved in bone maturation [IDA]
- cAMP-mediated signaling [TAS]
- cardiac muscle hypertrophy [IDA]
- cellular response to L-ascorbic acid [IEP]
- cellular response to retinoic acid [IEP]
- central nervous system neuron development [ISO]
- cholesterol metabolic process [ISO]
- circadian rhythm [IEP]
- eating behavior [ISO]
- energy reserve metabolic process [IDA]
- fatty acid beta-oxidation [ISO]
- fatty acid catabolic process [IDA]
- female pregnancy [IEP]
- glucose homeostasis [ISO]
- glucose metabolic process [ISO]
- glycerol biosynthetic process [IDA]
- hormone metabolic process [ISO]
- insulin secretion [ISO]
- intracellular signal transduction [IDA, TAS]
- leptin-mediated signaling pathway [IDA]
- leukocyte tethering or rolling [IDA]
- lipid metabolic process [ISO]
- negative regulation of apoptotic process [IDA]
- negative regulation of appetite [ISO, ISS]
- negative regulation of cartilage development [IDA]
- negative regulation of glucagon secretion [ISO]
- negative regulation of glutamine transport [IMP]
- negative regulation of metabolic process [IDA]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of vasoconstriction [IDA]
- ovulation from ovarian follicle [IDA]
- placenta development [ISO]
- positive regulation of JAK-STAT cascade [IMP, ISO]
- positive regulation of MAPK cascade [IDA]
- positive regulation of STAT protein import into nucleus [ISO]
- positive regulation of cell proliferation [IDA]
- positive regulation of cytokine production [IEP]
- positive regulation of developmental growth [ISO]
- positive regulation of follicle-stimulating hormone secretion [IEP]
- positive regulation of hepatic stellate cell activation [IDA]
- positive regulation of insulin receptor signaling pathway [IDA]
- positive regulation of ion transport [IDA]
- positive regulation of luteinizing hormone secretion [IEP]
- positive regulation of myeloid cell differentiation [ISO]
- positive regulation of peroxisome proliferator activated receptor signaling pathway [IDA]
- positive regulation of protein import into nucleus [ISO]
- positive regulation of reactive oxygen species metabolic process [IDA]
- positive regulation of tyrosine phosphorylation of Stat3 protein [IMP]
- regulation of blood pressure [IDA]
- regulation of fat cell differentiation [ISO]
- regulation of gluconeogenesis [ISO]
- regulation of insulin secretion [ISO]
- regulation of intestinal cholesterol absorption [ISO]
- regulation of lipoprotein lipid oxidation [IDA]
- regulation of metabolic process [ISO]
- regulation of protein localization to nucleus [ISO]
- regulation of protein phosphorylation [ISO]
- regulation of steroid biosynthetic process [ISO]
- response to dietary excess [IMP, ISO]
- response to hypoxia [IEP]
- response to insulin [ISO]
- response to nutrient [IEP]
- response to vitamin E [IEP]
- tyrosine phosphorylation of STAT protein [ISO]
Gene Ontology Molecular Function
Download Curated Data for this Protein
247637
10116
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- Interactors 5
- Interactions 6
- Network