Rattus norvegicus
NTRK1
Trk
neurotrophic tyrosine kinase, receptor, type 1
GO Process (42)
GO Function (9)
GO Component (13)
Gene Ontology Biological Process
- B cell differentiation [ISO]
- Sertoli cell development [IMP]
- aging [IEP]
- axon guidance [IMP]
- axonogenesis involved in innervation [ISO, ISS]
- cellular response to growth factor stimulus [IDA]
- cellular response to nerve growth factor stimulus [IDA]
- cellular response to nicotine [IDA]
- detection of mechanical stimulus involved in sensory perception of pain [IMP]
- detection of temperature stimulus involved in sensory perception of pain [IMP]
- developmental programmed cell death [IDA]
- learning or memory [IMP]
- mechanoreceptor differentiation [ISO]
- negative regulation of cell proliferation [ISO, ISS]
- negative regulation of neuron apoptotic process [IMP, ISO]
- negative regulation of neuron death [IDA]
- nerve growth factor signaling pathway [IDA, ISO]
- nervous system development [ISO]
- neurotrophin TRK receptor signaling pathway [ISO, ISS]
- olfactory nerve development [IEP]
- peptidyl-tyrosine phosphorylation [IDA, ISO, ISS]
- positive regulation of ERK1 and ERK2 cascade [ISO, ISS]
- positive regulation of NF-kappaB transcription factor activity [ISO, ISS]
- positive regulation of Ras GTPase activity [ISO, ISS]
- positive regulation of Ras protein signal transduction [ISO, ISS]
- positive regulation of angiogenesis [ISO]
- positive regulation of neuron projection development [ISO, ISS]
- positive regulation of programmed cell death [IDA]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- protein autophosphorylation [IDA, ISO]
- protein phosphorylation [ISO, ISS]
- response to activity [IDA]
- response to axon injury [IEP]
- response to drug [IDA]
- response to electrical stimulus [IDA]
- response to ethanol [IEP]
- response to hydrostatic pressure [IEP]
- response to nicotine [IDA]
- response to nutrient levels [IDA]
- response to radiation [IEP]
- sensory perception of pain [IMP]
- sympathetic nervous system development [ISO, ISS]
Gene Ontology Molecular Function- ephrin receptor binding [IPI]
- kinase binding [IPI]
- nerve growth factor binding [IDA, ISO, ISS]
- nerve growth factor receptor activity [ISO, ISS]
- neurotrophin p75 receptor binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [ISO, ISS]
- protein tyrosine kinase activity [IDA]
- transmembrane receptor protein tyrosine kinase activity [ISO, ISS]
- ephrin receptor binding [IPI]
- kinase binding [IPI]
- nerve growth factor binding [IDA, ISO, ISS]
- nerve growth factor receptor activity [ISO, ISS]
- neurotrophin p75 receptor binding [IPI]
- protein binding [IPI]
- protein homodimerization activity [ISO, ISS]
- protein tyrosine kinase activity [IDA]
- transmembrane receptor protein tyrosine kinase activity [ISO, ISS]
Gene Ontology Cellular Component
Download Curated Data for this Protein
248731
10116
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- Interactors 24
- Interactions 34
- Network
- PTM Sites 1