Rattus norvegicus
SHANK1
Shank1a, Spank1, Sstrip
SH3 and multiple ankyrin repeat domains 1
GO Process (19)
GO Function (11)
GO Component (12)
Gene Ontology Biological Process
- adult behavior [ISO]
- associative learning [ISO, ISS]
- cytoskeletal anchoring at plasma membrane [NAS]
- dendritic spine morphogenesis [ISO, ISS]
- determination of affect [ISO]
- habituation [ISO, ISS]
- long-term memory [ISO, ISS]
- negative regulation of actin filament bundle assembly [ISO, ISS]
- neuromuscular process controlling balance [ISO, ISS]
- olfactory behavior [ISO, ISS]
- positive regulation of dendritic spine development [IDA]
- positive regulation of excitatory postsynaptic membrane potential [ISO, ISS]
- protein complex assembly [IDA]
- protein localization to synapse [ISO, ISS]
- regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [ISO, ISS]
- righting reflex [ISO, ISS]
- social behavior [ISO]
- synapse maturation [IDA]
- vocalization behavior [ISO]
Gene Ontology Molecular Function- GKAP/Homer scaffold activity [IDA, ISO]
- SH3 domain binding [IPI]
- ankyrin repeat binding [IPI]
- identical protein binding [IPI]
- ionotropic glutamate receptor binding [IPI, ISO]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- protein complex binding [IPI]
- receptor signaling complex scaffold activity [IDA]
- scaffold protein binding [IPI]
- somatostatin receptor binding [IPI]
- GKAP/Homer scaffold activity [IDA, ISO]
- SH3 domain binding [IPI]
- ankyrin repeat binding [IPI]
- identical protein binding [IPI]
- ionotropic glutamate receptor binding [IPI, ISO]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- protein complex binding [IPI]
- receptor signaling complex scaffold activity [IDA]
- scaffold protein binding [IPI]
- somatostatin receptor binding [IPI]
Gene Ontology Cellular Component
- N-methyl-D-aspartate selective glutamate receptor complex [IDA]
- dendrite [ISO, NAS]
- dendritic spine [IDA, ISO]
- excitatory synapse [ISO, ISS]
- intracellular [NAS]
- ionotropic glutamate receptor complex [ISO, ISS]
- membrane [ISO]
- neuron projection [ISO, ISS]
- neuronal postsynaptic density [ISO, ISS]
- plasma membrane [ISO, ISS]
- postsynaptic membrane [IDA, ISO]
- synapse [IDA]
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- Interactors 6
- Interactions 11
- Network