Rattus norvegicus
SRC
SRC proto-oncogene, non-receptor tyrosine kinase
GO Process (83)
GO Function (22)
GO Component (16)
Gene Ontology Biological Process
- activation of protein kinase B activity [IMP]
- adherens junction organization [IDA]
- bone resorption [IBA, ISO, ISS]
- branching involved in mammary gland duct morphogenesis [ISO]
- cell migration [ISO]
- cell proliferation [IDA]
- cellular response to fatty acid [IEP]
- cellular response to hypoxia [IEP]
- cellular response to insulin stimulus [IEP]
- cellular response to lipopolysaccharide [IEP]
- cellular response to platelet-derived growth factor stimulus [ISO]
- cellular response to progesterone stimulus [IMP]
- cellular response to transforming growth factor beta stimulus [ISO]
- central nervous system development [IBA]
- epidermal growth factor receptor signaling pathway [IEP]
- forebrain development [ISO]
- innate immune response [IBA]
- integrin-mediated signaling pathway [ISO]
- intracellular estrogen receptor signaling pathway [IBA]
- intracellular signal transduction [ISO]
- negative regulation of anoikis [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of extrinsic apoptotic signaling pathway [IBA, ISO]
- negative regulation of focal adhesion assembly [IMP]
- negative regulation of intrinsic apoptotic signaling pathway [IBA, ISO]
- negative regulation of mitochondrial depolarization [ISO]
- negative regulation of protein homooligomerization [ISO]
- negative regulation of transcription, DNA-templated [IMP]
- neurotrophin TRK receptor signaling pathway [IDA]
- oogenesis [ISO]
- osteoclast development [IBA, ISO]
- peptidyl-serine phosphorylation [IMP]
- peptidyl-tyrosine autophosphorylation [IBA]
- peptidyl-tyrosine phosphorylation [ISO]
- positive regulation of DNA biosynthetic process [IMP]
- positive regulation of ERK1 and ERK2 cascade [IMP, ISO]
- positive regulation of MAP kinase activity [IMP]
- positive regulation of apoptotic process [IDA]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of cell adhesion [IDA]
- positive regulation of cyclin-dependent protein serine/threonine kinase activity [IMP]
- positive regulation of cytokine secretion [IMP]
- positive regulation of gene expression [IMP]
- positive regulation of glucose metabolic process [IMP]
- positive regulation of insulin receptor signaling pathway [IDA]
- positive regulation of intracellular signal transduction [IMP]
- positive regulation of phosphatidylinositol 3-kinase activity [IMP]
- positive regulation of platelet-derived growth factor receptor signaling pathway [IEP]
- positive regulation of podosome assembly [ISO]
- positive regulation of protein autophosphorylation [IMP]
- positive regulation of protein kinase B signaling [ISO]
- positive regulation of protein transport [IMP]
- positive regulation of smooth muscle cell migration [IMP]
- positive regulation of transcription, DNA-templated [IMP]
- progesterone receptor signaling pathway [IMP]
- protein autophosphorylation [IDA, ISO]
- protein phosphorylation [ISO]
- regulation of caveolin-mediated endocytosis [ISO]
- regulation of cell projection assembly [ISO]
- regulation of cell proliferation [IBA]
- regulation of cell-cell adhesion [ISO]
- regulation of early endosome to late endosome transport [ISO]
- regulation of epithelial cell migration [ISO]
- regulation of intracellular estrogen receptor signaling pathway [ISO]
- regulation of podosome assembly [IBA]
- regulation of protein binding [ISO]
- response to acidic pH [IEP]
- response to drug [IEP]
- response to electrical stimulus [IEP]
- response to fatty acid [IEP]
- response to hydrogen peroxide [IEP]
- response to interleukin-1 [ISO]
- response to mechanical stimulus [IEP]
- response to mineralocorticoid [IEP]
- response to nutrient levels [IEP]
- response to virus [IEP]
- single organismal cell-cell adhesion [IEP]
- stress fiber assembly [ISO]
- substrate adhesion-dependent cell spreading [ISO]
- transcytosis [IDA]
- transforming growth factor beta receptor signaling pathway [ISO]
- uterus development [ISO]
Gene Ontology Molecular Function- SH2 domain binding [ISO]
- cell adhesion molecule binding [IPI]
- enzyme binding [IPI, ISO]
- ephrin receptor binding [ISO]
- estrogen receptor binding [IPI]
- growth factor receptor binding [IBA, ISO]
- heme binding [ISO, ISS]
- insulin receptor binding [IPI]
- ion channel binding [ISO]
- kinase activity [ISO, TAS]
- non-membrane spanning protein tyrosine kinase activity [IBA]
- phosphoprotein binding [ISO]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- protein complex binding [IPI]
- protein domain specific binding [ISO]
- protein kinase C binding [IPI]
- protein kinase activity [ISO]
- protein kinase binding [IPI]
- protein tyrosine kinase activity [IDA, ISO]
- receptor binding [IPI, ISO]
- scaffold protein binding [ISO]
- SH2 domain binding [ISO]
- cell adhesion molecule binding [IPI]
- enzyme binding [IPI, ISO]
- ephrin receptor binding [ISO]
- estrogen receptor binding [IPI]
- growth factor receptor binding [IBA, ISO]
- heme binding [ISO, ISS]
- insulin receptor binding [IPI]
- ion channel binding [ISO]
- kinase activity [ISO, TAS]
- non-membrane spanning protein tyrosine kinase activity [IBA]
- phosphoprotein binding [ISO]
- protein C-terminus binding [IPI]
- protein binding [IPI]
- protein complex binding [IPI]
- protein domain specific binding [ISO]
- protein kinase C binding [IPI]
- protein kinase activity [ISO]
- protein kinase binding [IPI]
- protein tyrosine kinase activity [IDA, ISO]
- receptor binding [IPI, ISO]
- scaffold protein binding [ISO]
Gene Ontology Cellular Component
- actin filament [ISO]
- caveola [IDA, ISO]
- cytoplasm [ISO]
- cytosol [ISO, NAS, TAS]
- extracellular vesicular exosome [ISO]
- extrinsic component of cytoplasmic side of plasma membrane [IBA]
- intracellular [ISO]
- late endosome [ISO]
- lysosome [ISO]
- mitochondrial inner membrane [ISO, ISS]
- mitochondrion [ISO]
- neuron projection [IDA]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [IDA, ISO]
- postsynaptic density [IDA]
- ruffle membrane [ISO]
Download Curated Data for this Protein
249840
10116
Switch View:
- Interactors 18
- Interactions 24
- Network